{"title":"Arnold J Levine","description":null,"products":[{"product_id":"viruses-book-arnold-j-levine-9780716750314","title":"Viruses","description":"Since the isolation of the first virus in 1892 scientists have made tremendous advances by asking one question at a time and building on the answers. Dr. Levine celebrates the successes that have come from viral studies - the development of a wide range of vaccines, the eradication of smallpox, and the insights into the origins of cancer. He also examines the challenges we still face, with a series of interconnected chapters on the specific viruses behind some of our most urgent public health problems, including the viruses that cause AIDS, influenza, herpes and hepatitis. A concluding chapter on the origin and evolution of viruses touches on some of the most provocative issues in molecular biology today. Viral infections continue to be an immediate health concern of imposing proportions. \"Viruses\" is written for the general reader eager to know how we study and confront these diseases and where today's research may lead.","brand":"WoB","offers":[{"title":"GB \/ VERY_GOOD \/ INTERNAL","offer_id":49611680579857,"sku":"GOR001419991","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ GOOD \/ SBYB","offer_id":50026149347601,"sku":"CIN0716750317G","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ WELL_READ \/ SBYB","offer_id":50170285261073,"sku":"CIN0716750317A","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ VERY_GOOD \/ SBYB","offer_id":50243013116177,"sku":"CIN0716750317VG","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ WELL_READ \/ INTERNAL","offer_id":50554568802577,"sku":"GOR013578389","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0716750317.jpg?v=1751137580"},{"product_id":"p53-family-book-arnold-j-levine-9780879698300","title":"The P53 Family","description":null,"brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52478111547665,"sku":"NLS9780879698300","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780879698300.jpg?v=1759846668"},{"product_id":"p53-protein-from-cell-regulation-to-cancer-book-arnold-j-levine-9781621821335","title":"The P53 Protein: From Cell Regulation to Cancer","description":"Decades of research on the tumor suppressor p53 have revealed that it plays a significant role as a guardian of the genome, protecting cells against genotoxic stress. In recent years, p53 research has begun to move into the clinic in attempts to understand how p53 is frequently inactivated in-and sometimes even promotes-human cancer. \u003cp\u003e\u003c\/p\u003eWritten and edited by experts in the field, this collection from \u003cem\u003eCold Spring Harbor Perspectives in Medicine\u003c\/em\u003e covers the rapid progress that has recently been made in basic and clinical research on p53. The contributors review new observations about its basic biology, providing updates on the functions of its isoforms and domains, the myriad stresses and signals that trigger its activation or repression, and its downstream effects on genome stability and the cell cycle that enforce tumor suppression in different cell and tissue types. They also discuss how p53 dysfunction contributes to cancer, exploring the various inherited and somatic mutations in the human \u003cem\u003eTP53\u003c\/em\u003e gene, the impact of mutant p53 proteins on tumorigenesis, and the prognostic value and clinical outcomes of these mutations. \u003cp\u003e\u003c\/p\u003eDrugs that are being developed to respond to tumors harboring aberrant p53 are also described. This book is therefore essential reading for all cancer biologists, cell and molecular biologists, and pharmacologists concerned with the treatment of this disease.\u003cbr\u003e","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52821158002961,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52821158166801,"sku":"NLS9781621821335","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781621821335.jpg?v=1764331422"}],"url":"https:\/\/www.worldofbooks.com\/collections\/author-books-by-arnold-j-levine.oembed","provider":"World of Books ","version":"1.0","type":"link"}