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We now know that the central nervous system is both a target and a production site of many hormonal products, and that hormones, neurotransmitters, growth factors and immunopeptides all act through similar mechanisms. The only second messenger known ten years ago was cAMP; today calcium, derivatives of membrane phospholipids, and protein kinases are also known to be mediators of hormone action. The very concept of hormonal systems has been expanded to include not only endocrine secretions but also para- and autohormones and their mechanisms of action; an understanding of their functions will be central to the immediate future of medicine. The discovery of hormonal molecules and endocrine interactions and the subsequent understanding of hormone­ related pathophysiology has led to the development of new strategies in medical treatment such as fertility control and the management of diabetes.","brand":"WoB","offers":[{"title":"US \/ GOOD \/ SBYB","offer_id":50349147357457,"sku":"CIN0412027917G","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52144226173201,"sku":"NLS9780412027918","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52735273861393,"sku":"NIN9780412027918","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0412027917.jpg?v=1750740000"},{"product_id":"abortion-pill-book-etienne-emile-baulieu-9780712656214","title":"The Abortion Pill","description":"The book about the most controversial medical discovery of recent years - the unpregnancy pill - as described by the scientists who created it.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":50434447835409,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ VERY_GOOD \/ INTERNAL","offer_id":50434447999249,"sku":"GOR005372672","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0712656219.jpg?v=1750977304"},{"product_id":"antiprogestin-steroid-ru-486-and-human-fertility-control-book-etienne-emile-baulieu-9781468412444","title":"The Antiprogestin Steroid RU 486 and Human Fertility Control","description":"Advances in basic biological research have proceeded rapidly in recent years. The fields of molecular genetics and immunology have experienced dramatic breakthroughs, capturing the imagination of both the scientific community and the general public. With less public notice, receptor biology has brought a cascade of new discoveries and insights. The entire science of pharmacology has been virtually rewritten in terms of receptor phenomenology. In particular, the discovery of specific receptors for steroid and protein hormones has been of seminal importance. With this new information, we have advanced our understanding of the mechanism and specifity of hormone action. We can now explain how hormones interact selectively with specific target cells and how hormones alter biochemical events within the target cells. These facts have already impacted on applied problems of clinical medicine, particularly in diagnosis and treatment of cancer and some metabolic diseases. Now, a new and important application of basic receptor biology and chemistry looms ahead. Within a few short years since the discovery of the progesterone receptor, chemists have synthesized molecules with a greater affinity for the receptor than progesterone itself and which, while occupying the receptor, fail to trigger the events which transform a target cell from the unstimulated to the stimulated state. This is the basis of the competitive inhibitory action of the anti-progestational agent, synthesized by the chemists at Roussel Uc1af, Paris, and designated RU 486.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52337851695377,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52337852252433,"sku":"NLS9781468412444","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781468412444.jpg?v=1758167982"},{"product_id":"ru-486-die-abtreibungspille-book-etienne-emile-baulieu-9783540579021","title":"RU 486 Die Abtreibungspille","description":"ber RU 486, die Abtreibungspille aus Frankreich, ist viel diskutiert und noch mehr polemisiert worden. Der franz sische Hormonforscher Etienne-Emile Baulieu, der den Wirkstoff entdeckt hat, legt in diesem Buch Rechenschaft ab:  ber seine Forschungen, seine Motive und  berzeugungen, aber auch seine Zweifel. Er weicht der moralischen Diskussion um die Abtreibung nicht aus, doch im Mittelpunkt seines Buches stehen die Etappen der Hormonforschung, die schlie lich zur Entwicklung von RU 486 gef hrt haben. Leicht nachvollziehbar wird erkl rt, welchen Einflu  die Hormone auf die Entstehung der Schwangerschaft haben und warum RU 486 zum Schwangerschaftsabbruch f hrt. Die medizinischen Erfahrungen mit dem Pr parat werden ebenso ausf hrlich geschildert wie der Kampf um die Marktzulassung. Die deutsche Diskussion  ber RU 486 fa t Professor Christian Lauritzen in einem Nachwort zusammen. F r interessierte Laien, Gyn kologen","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52341464760593,"sku":"NLS9783540579021","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52761663176977,"sku":"NIN9783540579021","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9783540579021.jpg?v=1758171713"},{"product_id":"neurosteroids-book-etienne-emile-baulieu-9781617370687","title":"Neurosteroids","description":"Etienne-Emile Baulieu, the discoverer of neurosteroids, and a panel of distinguished scientists and clinical researchers exhaustively and critically review all facets of neurosteroids involved in behavior, stress, memory, depression, anxiety, aging of the brain, and neurodegenerative diseases. These contributors illuminate the role of neurosteroids in brain development and plasticity and detail their neuromodulatory  influence on GABAA, ionotropic glutamate receptors, acetylcholine receptors, sigma receptors, and calcium channels. Clearly pointing the way toward novel pharmaceutical agents that may be of significant therapeutic value, particularly with regard to aging mental functions, Neurosteroids: A New Regulatory Function in the Nervous System offers neurobiologists, psychiatrists, neurosurgeons, pharmacologists, and geriatricians the first comprehensive, state-of-the-art review of these important bioactive molecules.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52455604977937,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52455605534993,"sku":"NLS9781617370687","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781617370687.jpg?v=1759374796"},{"product_id":"neurosteroids-book-etienne-emile-baulieu-9780896035454","title":"Neurosteroids","description":"Etienne-Emile Baulieu, the discoverer of neurosteroids, and a panel of distinguished scientists and clinical researchers exhaustively and critically review all facets of neurosteroids involved in behavior, stress, memory, depression, anxiety, aging of the brain, and neurodegenerative diseases. 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