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This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52141013336337,"sku":"NLS9789400704275","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789400704275.jpg?v=1757576284"},{"product_id":"cell-cycle-synchronization-book-gaspar-banfalvi-9781493966028","title":"Cell Cycle Synchronization","description":"This second edition volume provides detailed protocols on the theoretical background of cell cycle synchronization procedures and instructions on how to implement these techniques. The chapters in Cell Cycle Synchronization: Methods and Protocols, Second Edition cover subjects such as: physical fractionations including centrifugal elutriation of healthy and apoptotic cells, and nuclei of mammalian cells; large scale mitotic cell synchronization; chromosome formation during fertilization in eggs; synchronization of unicellular organisms; hematopoietic stem cells used to improve the engraftment in transplantation; and cell cycle control. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Practical and comprehensive, Cell Cycle Synchronization: Methods and Protocols, Second Edition is a valuable resource for PhD students and postdoctoral fellows, and researchers interested in general science, pharmacy, medicine and public health, computer science, and life sciences. Specialists and professionals in cell biology, genetics, molecular biology, biochemistry, and pharmacology will also find this book useful.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52142115356945,"sku":"NLS9781493966028","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781493966028.jpg?v=1757579278"},{"product_id":"apoptotic-chromatin-changes-cd-9781402095603","title":"Apoptotic Chromatin Changes","description":"The writing of this book is based on: 1. earlier experience writing textbooks for biology students with a university-level background in biology and biochemistry with many (\u0026gt;200) ?gures in these books (in Hungarian), 2. and on the necessity to present university lectures as power point presentations to catch the interest of s- dents. The author realizes that young readers who were grown up in an information society are relactant to read too much unless they have to take exams. Even then they prefer books which contain illustrations for a better understanding. In collaboration with colleagues, referees and members of the publishing staff an extensive set of photographs and illustrations were collected to provide a graphic follow-up to the text. Further aids for the student, instructor and the curious reader are provided by summaries, extensive sets of readings and references for each chapter, a glossary of the terms, list of abbreviations and a DVD with a red-blue eyeglass to visualize three dimensional chromatin structures. The reader could ask: Why another book on apoptosis? The answer to the question is related to the de?nition of the process. The term apoptosis has been introduced to describe typical morphological changes leading to controlled se- destruction of cells. The ?rst demonstrated biochemical feature of this type of cell death was internucleosomal fragmentation, which was occasionally preceded by the generation of large DNA fragments.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52146853085457,"sku":"NLS9781402095603","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781402095603.jpg?v=1757598644"},{"product_id":"cellular-effects-of-heavy-metals-book-gaspar-banfalvi-9789400792258","title":"Cellular Effects of Heavy Metals","description":"The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g\/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52335885943057,"sku":"NLS9789400792258","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789400792258.jpg?v=1758161514"},{"product_id":"apoptotic-chromatin-changes-book-gaspar-banfalvi-9789401777247","title":"Apoptotic Chromatin Changes","description":"The writing of this book is based on: 1. earlier experience writing textbooks for biology students with a university-level background in biology and biochemistry with many (\u0026gt;200) ?gures in these books (in Hungarian), 2. and on the necessity to present university lectures as power point presentations to catch the interest of s- dents. The author realizes that young readers who were grown up in an information society are relactant to read too much unless they have to take exams. Even then they prefer books which contain illustrations for a better understanding. In collaboration with colleagues, referees and members of the publishing staff an extensive set of photographs and illustrations were collected to provide a graphic follow-up to the text. Further aids for the student, instructor and the curious reader are provided by summaries, extensive sets of readings and references for each chapter, a glossary of the terms, list of abbreviations and a DVD with a red-blue eyeglass to visualize three dimensional chromatin structures. The reader could ask: Why another book on apoptosis? The answer to the question is related to the de?nition of the process. The term apoptosis has been introduced to describe typical morphological changes leading to controlled se- destruction of cells. The ?rst demonstrated biochemical feature of this type of cell death was internucleosomal fragmentation, which was occasionally preceded by the generation of large DNA fragments.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52451382001937,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52451382690065,"sku":"NLS9789401777247","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401777247.jpg?v=1759361416"},{"product_id":"permeability-of-biological-membranes-book-gaspar-banfalvi-9783319802718","title":"Permeability of Biological Membranes","description":"This book deals with biological membranes, focuses on permeabilization and pays particular attention to reversible permeabilization to maintain the viability and physiological conditions of the cells.  Selective permeability of biological membranes also known as semipermeability, partial permeability or differential permeability allows molecules to diffuse, pass by passive and active or by other types of transport processes mediated by proteins.   The first chapter of the book deals with the composition of biological membranes, characterizes cellular membranes of prokaryotic, eukaryotic cells, membranes of cellular organelles and the function of biological membranes. The second chapter provides an overview of bilayer permeability, selectivity of permeabilization and cellular transport processes. Chapter 3 overviews different cell manipulations that aim to make cells permeable while maintaining not only the structural but also the functional integrity of cells. The last chapter deals with applications, particularly with reversible permeabilization to study macromolecular (DNA, RNA, poly-ADP ribose) biosynthetic processes, replication, gene expression, visualization of replicons, intermediates of chromosome condensation, genotoxic chromatin changes, upon treatment with heavy metals and different types of  irradiation.            The interdisciplinary aspects of the book contribute to the understanding of the structure of nucleic acids, replicative intermediates, Okazaki fragments, RNA primer mechanism, subphases of replication and repair synthesis, replicons, gene expression, chromosome condensation generated a wealth of information that will attract a wide readership. 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