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His latest book provides an innovative look at the experimental protocols and connections that have made the life sciences so productive.\u003cbr\u003e  \u003cbr\u003e Delving into the materiality of the experiment, the first part of the book assesses traces, models, grafting, and note-taking—the conditions that give experiments structure and make discovery possible. The second section widens its focus from micro-level laboratory processes to the temporal, spatial, and narrative links between experimental systems. Rheinberger narrates with accessible examples, most of which are drawn from molecular biology, including from the author’s laboratory notebooks from his years researching ribosomes.\u003cbr\u003e  \u003cbr\u003e A critical hit when it was released in Germany, \u003ci\u003eSplit and Splice \u003c\/i\u003edescribes a method that involves irregular results and hit-or-miss connections—not analysis, not synthesis, but the splitting and splicing that form a scientific experiment. 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Bachelard was a philosopher and historian of science who was also involved in literary studies and poetics. Flocon was a student of the Bauhaus in Dessau, Germany, who specialized in copper engraving. Both deeply ingrained in the surrealist avant-garde movements, each acted at the frontiers of their respective m tiers in exploring uncharted territory. Bachelard experienced the sciences of his time as constantly undergoing radical changes, and he wanted to create a historical epistemology that would live up to this experience. He saw the elementary gesture of the copper engraver-the hand of the engraver-as meeting the challenge of resistant and resilient matter in an exemplary fashion. Flocon was fascinated by Bachelard's unconventional approach to the sciences and his poetics. Together, their relationship interrogated and celebrated the interplay of hand and matter as it occurs in poetic writing, in the art of engraving, and in scientific experimentation. 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