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Ovidius Tristium Lib. II 266.  . 1. Die Angriffspnnkte fiir die Arzlleiwirkung . . Die Arzneimittel beeinflussen je nach ihrer cheniischen oder physi- kalIschen Eigenart gewisse Klassen von Zellen oder zellenartigen Gebilden besonders oder ausschliesslich, k nnen aber auch nur auf Blutserum, zellenlose K rpers fte oder . Krankheitsproducte wirken. So behindern z. B. Galle oder ein Aufguss von Radix Sarsaparillae energisch die Pepsinwirkung, w hrend sie' die Wirkung der meisten  brigen Fermente sich ungehindert abspielen lassen. Manche Farbstoffe suchen sich nur bestimmte Zellen zur Ablagerung auf. Dagegen entziehen S uren allen alkalischen K rpers ften das Alkali. Die Beziehungen . von Stoffen zu bestimmten K rpertheilen ist eine bereits von alten Aerzten ausge- sprochene Fundamentalanschauung. Aus ihr ergiebt sich als Folgerung, dass gewisse Mittel ausser dem Heileffect noch Symptome veranlassen k nnen, die von einer Einwirkung auf Zellgruppen oder sonstige K rper- bestandtheile, welche 'therapeutisch nicht getroffen werden sollten, her- r hren. So werden nach dem Darreichen von Opium gewisse centrale und peripherische Nervencentren oder Nerven beeinflusst, und es kommt derugem ss neben einer hypnotischen Wirkung eine L hmung der Darlll- bewegung zu Stande. Giebt man innerlich Brechweinstein, so entsteht in Folge der Reizung der Magenschleimhaut Erbrechen. Ausserdem wird aber durch eine muskul re Einwirkung die Th tigkeit des Herzens herabgesetzt. W hrend also beim Opium gleichartige Elemente nerv ser Natur in ver- schiedenen K rperregionen Ver nderungen erleiden, werrlen durch das Antimon verschiedenartige Elemente, n mlich Schleimhiiute und Muskeh1, beeinflusst. 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Wenn nun der Akademie-Verlag Berlin hier erstmals das Reise- tagebuch einer USA-Canada-Reise von Louis Lewin der 6fTent- lichkeit zugangig macht, so vermittelt er damit nieht nur einen interessanten kultur-geschichtlichen Einblick in die Reisekul- tur vor nahezu einhundert Jahren, er gibt damit vor aHem auch ein liebenswertes Personlichkeitsbild dieses so au8erordentlich kenntnisreichen und zeitkritischen Toxikologen. Wir begrii8en es auBerordentlich, daB die Koniglich-Schwedische Akademie der Wissenschaften gemeinsam mit der Akademie der Wissenschaften der DDR die von den beiden Herausgebem begriindete Zusammenarbeit in der Erschliessung des Erbes von Louis Lewin nach der Durchfiihrung des Lewin-Symposiums am 23. 10. 1981 in Berlin nun mit dieser ErstverofTentlichung des Lewinschen Reisetagebuches fortsetzt. Wir wiinschen diesen Be- miihungen weiteren Erfolg. 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Die Hoffnung ist gesunken, das Wesen dieses Unbegreiflichen auf dem Weg deduktiver Spekulation zu begreifen. Und selbst wenn es dem je gelingen sollte, was meiner Ansicht nach menschlichen Geiste stets nur eine Hoffnung bleiben wird, die letzten Ursachen des Entstehens, Le bens und Vergehens einer Zelle analytisch zu erkennen, so wiirde das Geheimnis der Individualitat mit ihren unendlich zahlreichen funktionellen AuBerungsformen, die an jede Zelle oder jede Zellengemeinschaft gebunden sein konnen, den Forscher vor weitere millionenfache Probleme stellen, von denen jedes zu lOsen so schwierig sein wiirde, wie die Enthiillung des Wesens des normalen Zellebens. . Und doch muB immer wieder der Versuch gemacht werden, dem begrifflich UnfaBlichen dadurch wenigstens naherzukommen, daB man seine AuBerungen kennenlernt, falls solche vorhanden sind. -Der gezwungene Verzicht auf volle Erkenntnis bedingt nicht den Verzicht auf Forschung. Den ersten groBeren Versuch, auf induktivem Wege Licht-in dieses dunkle Gebiet zu bringen, habe ich in meinem Handbuch Die Nebenwirkungen der Arzneimittel gemacht, dessen Zweck wesentlich war, eine kritische Bearbeitung derjenigen Arzneiwirkungen zu geben, die auf dem Boden einer besonderen Disposition erwachsen, und da- durch dem weiteren Eindringen in die hierbei au tauchenden Fragen den Weg zu ebnen.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52661033402641,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52661033959697,"sku":"NLS9783662275450","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9783662275450.jpg?v=1762266542"}],"url":"https:\/\/www.worldofbooks.com\/collections\/author-books-by-louis-lewin.oembed","provider":"World of Books ","version":"1.0","type":"link"}