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This again became clear during the COVID-19 pandemic and is evinced in the sustainability crisis. The dynamics of living matter transcends deterministic reaction. Embodied in machines, determinism empowered the human being, providing the path to prosperity. However, in  conjunction with reductionism, it does away with complexity, in which life is couched.\u003c\/p\u003e\n\n\u003cp\u003eThe living is by necessity anticipatory. Awareness of the future means preserving life not in reaction to, but in anticipation of change. Living entities, from the simplest bacteria, to plants and insects, to human beings, are adaptive, goal-oriented, and capable of self-healing. Anticipatory actions are expressed through non-deterministic processes that unfold in concert with reactions. They engage the wholeness of life, including its interactions with the environment. Awareness of consequences, together with memory of the past, informs actions that reflect the creative nature of human beings. 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The record of breakdowns (including so-called natural disasters), by now global in scale, is part of the empirical premise for the call for completing the Cartesian Revolution. A “Second Revolution in Science” could unleash humanity’s remaking, free of surrendering to want. 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The reader is presented with a provocative hypothesis: If medicine will align itself with the anticipatory condition of life, it can prompt the most important revolution in our time. To this end, all stakeholders—medical practitioners, patients, scientists, and technology developers—will have to engage in the conversation. The book makes the case for the transition from expensive, and only marginally effective, reactive treatment through “spare parts” (joint replacements, organ transplants) and reliance on pharmaceuticals (antibiotics, opiates) to anticipation-informed healthcare. \u003c\/p\u003e\n\n\u003cp\u003eReaders will understand why the current premise of treating various behavioral conditions (attention deficit disorder, hyperactivity, schizophrenia) through drugs has to be re-evaluated from theperspective of anticipation. In the manner practiced today, medicine generates dependence and long-lasting damage to those it is paid to help. 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