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Miller shares wisdom from experts on the frontiers of psychedelic research and palliative care—including Roland Griffiths, Katherine MacLean, Ira Byock, and Anthony Bossis—and examines cutting-edge studies from Johns Hopkins, UCLA, and NYU School of Medicine that show dramatically decreased anxiety in terminally ill patients through the use of psychedelics. He explores how different substances can help the dying overcome their end-of-life distress. He also provides testimony from researchers and patients participating in psychedelic-assisted psychotherapy that helps convey the experience of ego death at the heart of the psychedelic experience.  Miller outlines 10 steps for dying gracefully, without fear, with the help of psychedelics. He examines how to navigate the complex legal landscape and find the right guide, dose, and therapy. He also includes reflections from key figures in the psychedelic community as well as some of his own psychedelically informed mystical and near-death experiences.  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With the potential to reduce our reliance on pharmaceuticals and improve overall well-being, the use of psychedelics has yielded promising results. However, the increased acceptance and use of these age-old medicines should also be approached with caution and full awareness.  Clinical psychologist Richard Louis Miller provides a balanced analysis of the risks and benefits of psychedelics to ensure their responsible use. He comprehensively details the rewards and potential complications of substances like LSD, psilocybin, ayahuasca, DMT, MDMA, and ketamine to provide thorough risk profiles and a working guide for psychedelic-informed therapy.  Drawing on the latest research, interviews with practitioners, and case studies, Dr. Miller considers physiological effects like nausea, altered heart rate, and blood pressure changes, along with mental effects such as anxiety, reality distortion, and mood disorders often associated with a bad trip. 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