{"title":"Sylvester Noble","description":null,"products":[{"product_id":"gene-therapy-therapeutic-mechanisms-and-strategies-book-sylvester-noble-9781632418470","title":"Gene Therapy: Therapeutic Mechanisms and Strategies","description":"Gene therapy is a therapeutic technique in which nucleic acid is delivered into the cells of a patient as a drug to treat disease. The fundamental strategy in gene therapy is the use of DNA which when administered, reaches the damaged cells, enters the cell, and disrupts or expresses a protein. Multiple delivery techniques can be used for DNA delivery. Recent advances in the understanding of nuclease function have enabled direct DNA editing using CRISPR and zinc finger nucleases. Genes are incorporated into chromosomes with the help of vectors, which then express the nucleases that knock out and replace the genes in the chromosome. The vectors used in gene therapy can be recombinant viruses or naked DNA or DNA complexes. There is thus a great potential in using gene therapy and gene editing in treating genetic and viral diseases as well as cancer. The ever growing need of advanced diagnostic and therapeutic technology is the reason that has fueled the research in the field of gene therapy in recent times. The various studies that are constantly contributing towards advancing therapeutic strategies and mechanisms, and evolution of gene therapy are examined in detail. This book aims to serve as a resource guide for students and experts alike and contribute to the growth of the discipline.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51040609861905,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51040612745489,"sku":"NIN9781632418470","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1632418479.jpg?v=1751409398"},{"product_id":"gene-therapy-biomedical-applications-book-sylvester-noble-9781632428929","title":"Gene Therapy: Biomedical Applications","description":"In the field of medicine, the emerging frontier of gene therapy holds great potential in the treatment of many human diseases and conditions. It is characterized by the intent of direct therapeutic effect and the precision of the procedure. In this model, nucleic acid is delivered into a patient's cells which results in the replacement or knocking out of genes that cause a disease. Gene therapy can be classified into somatic and germline gene therapy. In somatic cell gene therapy, therapeutic genes are transferred into the somatic cells of the body and the resulting modifications affect the patient only, without being passed on to the offspring. In germline gene therapy, the germline itself is modified due to the introduction of functional genes into the genome of germ cells. Such changes are inherited by generations of individuals. This book covers in detail some existing theories and innovative concepts revolving around gene therapy. Some of the diverse topics covered in this book address the varied biomedical applications of gene therapy. As this field is emerging at a fast pace, this book will help the readers to better understand the advanced concepts of this field.","brand":"WoB","offers":[{"title":"US \/ NEW \/ INGRAM","offer_id":52752405823761,"sku":"NIN9781632428929","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781632428929.jpg?v=1763561475"}],"url":"https:\/\/www.worldofbooks.com\/collections\/author-books-by-sylvester-noble.oembed","provider":"World of Books ","version":"1.0","type":"link"}