{"title":"Ying Yuan","description":null,"products":[{"product_id":"bayesian-designs-for-phase-i-ii-clinical-trials-book-ying-yuan-9781498709552","title":"Bayesian Designs for Phase I-II Clinical Trials","description":"\u003cp\u003eReliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBayesian Designs for Phase I–II Clinical Trials\u003c\/strong\u003e describes how phase I–II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes.\u003c\/p\u003e\u003cp\u003eWritten by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity. \u003c\/p\u003e","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51242627563793,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51242629103889,"sku":"NIN9781498709552","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52144952377617,"sku":"NLS9781498709552","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1498709559.jpg?v=1791940240"},{"product_id":"model-assisted-bayesian-designs-for-dose-finding-and-optimization-book-ying-yuan-9780367146245","title":"Model-Assisted Bayesian Designs for Dose Finding and Optimization","description":"This book shows how model-assisted designs can greatly improve the efficiency and simplify the conduct of early-phase dose finding and optimization trials. It should therefore be a very useful practical reference for biostatisticians, clinicians working in clinical trials, and drug regulatory professionals, as well as grad students.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":53657341460753,"sku":"NLS9780367146245","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780367146245.jpg?v=1791952739"}],"url":"https:\/\/www.worldofbooks.com\/collections\/author-books-by-ying-yuan.oembed","provider":"World of Books ","version":"1.0","type":"link"}