{"title":"Immunology And Medicine","description":"\u003cp\u003eDelve into the fascinating fields of immunology and medicine with our curated book series collection. Explore the latest research, classic texts, and essential guides for students and professionals alike. Start your journey today.\u003c\/p\u003e","products":[{"product_id":"phagocytes-and-disease-book-ms-klempner-9780746200865","title":"Phagocytes and Disease","description":null,"brand":"WoB","offers":[{"title":"GB \/ WELL_READ \/ INTERNAL","offer_id":49647445180689,"sku":"GOR011789924","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0746200862.jpg?v=1750848141"},{"product_id":"immunology-of-hiv-infection-book-gr-bird-9780792389620","title":"Immunology of HIV Infection","description":"It is now 10 years since the first AIDS cases were reported in the USA. In that relatively short period of time, study of the disease has moved from the level of early clinical description to exhaustive and extensive laboratory characterization of the human immunodeficiency virus (HIV), the immune responses directed towards it and reasons for their failure. This volume provides contributions from clinical and basic scientists who are actively involved in research in a number of areas of current interest and controversy. Further progress in the clinical management of the HIV-infected patient will undoubtedly build on the basic knowledge about HIV and its modes of pathogenesis. The intimate relationship between HIV and the human immune system provides observations and questions that are relevant to viral immunopathogenesis in general. In the first chapter the clinical features of HIV immunodeficiency are re­ viewed, and aspects of its changing face are discussed. Dr Tersmette then presents evidence for changing viral characteristics at different stages of the disease. This view of close competition for ascendancy between HIV and the host immune response raises questions about current approaches to therapy.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ GARDNERS","offer_id":49729477247249,"sku":"NGR9780792389620","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52337800741137,"sku":"NLS9780792389620","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/079238962X.jpg?v=1750946734"},{"product_id":"lymphoproliferative-diseases-book-db-jones-9789401068178","title":"Lymphoproliferative Diseases","description":"Recent developments in the field of cellular pathology and molecular biology have had a major impact on our ability to diagnose lymphoreticular disease and on our understanding of many of the disease processes which contribute to lymphoreticular pathology. Twenty years ago, the immunological analysis of lymphoid proliferations was in its infancy. The techniques available, such as sheep red blood cell rosetting and immune adherence to frozen sections, now appear unbelievably crude when compared with our ability to accurately phenotype lymphocytes in suspension, in frozen section and, more recently, in formalin-fixed, paraffin-embedded tissue biopsies. Four international work- shops have also standardized the nomenclature for the wide range of lineage- restricted and lineage-related monoclonal antibodies available, and have provided a basis for the sophisticated phenotypic analysis of lymphoid neoplasms in even the smallest routine laboratories. Our concepts relating to the pathogenesis of a number of human lymphomas have also changed substantially, and this has been aided by the development of systems for the classification of human lymphoma which are firmly based in our knowledge of the differentiation and biological behaviour of normal lymphoreticular cells. In this monograph, we present contributions from many authors examining both leukaemia and lymphoma from an immunological perspec- tive. It is our hope that some of these contributions will be of practical value in the laboratory investigation and diagnosis of lymphoreticular disease. Other contributions record our conceptual understanding of the histogenesis and pathogenesis of human lymphoma.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52126626775313,"sku":"NLS9789401068178","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401068178.jpg?v=1757477476"},{"product_id":"immunoglobulins-in-health-and-disease-book-m-french-9789401083515","title":"Immunoglobulins in Health and Disease","description":"Rapid advances continue to be made in all areas of immunology, not least the biology of the immunoglobulins. This knowledge has resulted in a better understanding of antibody responses and helped to clarify pathogenic mechanisms in many diseases, particularly autoimmune and allergic diseases, as well as expand our comprehension of antibody deficiency diseases and mechanisms in therapeutic immunization. In addition, the recognition that diverse disease states may result in abnormalities of the amount of immunoglobulins in body fluids has resulted in the use of immunoglobulin assays for disease diagnosis and management. The aim of this book has been to condense both the established and recent aspects of this knowledge, particularly that pertaining to clinical immunology. The contributions of different authors hopefully provide a comprehensive review of their particular field of interest as well as a discussion of how this information can be applied to clinical medicine. Immunological terms and concepts have been explained where appropriate so that the book can be read by those with only a basic knowledge of immunology. In producing a book on this one area of immunology some duplication of information has been accepted so that topics can be considered in different contexts. I hope the book will be of value to those in training or already pursuing a career in clinical or laboratory medicine by providing a basic and short text on immunoglobulins. M.A.H.F.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52126760141073,"sku":"NLS9789401083515","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401083515.jpg?v=1757479510"},{"product_id":"immunology-of-pregnancy-and-its-disorders-book-cm-stern-9789401070539","title":"Immunology of Pregnancy and its Disorders","description":"The purpose of this book is to describe the nature of the materno-fetal immunobiological relationship and to suggest the direction in which the management of reproduction and its failure in man is moving. The several authors, who have written about their special fields of interest, need to be read within a framework designed to blend their contributions into a whole. This preamble provides a part of that framework, by describing the early development of the embryo, that of the placenta and its membranes and their anatomical relationship with maternal tissues: in other words, the stage upon which this materno-fetal dialogue takes place. Professor Maureen Young's 'tour de force', encapsulating the whole of fetal physiology into a single chapter, completes the background information. After Maureen Young's summary of fetal physiology, Matteo Adinolfi describes the development of the immune system in the fetus, including new information that allows more accurate speculation concerning the gestational age at which fetal immune responses of various kinds may begin. Charles Loke examines the nature of antigens which are found in the placenta, concentrating on those which occur on syncytiotrophoblast and suggesting roles for them in fetal development. Arnold Klopper covers the wide range of proteins and hormones which have been studied during pregnancy and found to vary in a potentially significant way. He has been careful to distinguish between observation and hypothesis, as far as any immunomodulating action is concerned, and his analysis is a model of scientific scepticism.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52126803427601,"sku":"NLS9789401070539","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401070539.jpg?v=1757480075"},{"product_id":"mast-cells-mediators-and-disease-book-stephen-t-holgate-9789401070720","title":"Mast Cells, Mediators and Disease","description":"In 1879 Paul Ehrlich first described the mast cell as a tissue fixed cell contain- ing many granules which, when stained with basic dyes, such as toluidine blue, changed the colour spectrum of the dye in a process called meta- chromasia. Since this early description, pathologists, physicians and pharmacologists have been fascinated by this cell on account of its central involvement in human allergic diseases. Approximately four decades after Ehrlich's first description of the mast cell, Prausnitz and Kiistner reported their pioneer experiment, demonstrating that the immediate skin wheal response to allergen could be passively transferred with serum. They named the antigen-specific serum factor reagin. A further four and one half decades had to pass before the connection between the mast cell and reagin could be made with the identification of reagin as an immunoglobulin E by Johansson and Ishizaka and its unique property to bind with high affinity to specific receptors on mast cells and basophils. Meanwhile in the 1920s Coca published a series of papers in which he described the clinical features of acute allergic responses and first used the term atopy. This, together with the fundamental pharmacological studies of Sir Henry Dale in identifying histamine as one mediator of the acute ana- phylactic reaction, provided the second approach which eventually linked the mast cell to allergic tissue reactions. Indeed, it was Best, working in Dale's group who first showed that histamine was a chemical stored in mast cells.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52128165593361,"sku":"NLS9789401070720","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401070720.jpg?v=1757489689"},{"product_id":"immunodeficiency-and-disease-book-adb-webster-9789401070669","title":"Immunodeficiency and Disease","description":"The AIDS epidemic has popularized immune deficiency and has led to a rapid increase in the funding for research into the effect of viruses on immunity. There is now a real possibility of finding out whether some of the rare, so-called 'primary' immunodeficiency syndromes of children and adults, first described in the 1950s, may have a viral aetiology. Most of these syndromes have already been extensively reviewed more than once over the past 10 years, and their diagnosis and management is now included in most standard medical textbooks. In this volume, I have chosen to highlight what I consider to be the potentially exciting aspects of immunodeficiency in humans, hopefully providing clinicians and medical academics with some insight into the recent breakthroughs and disappointments. There are three chapters discussing viral interactions with the immune system. Although much has been written about AIDS already, I make no apology for including an extensive review of both the clinical and laboratory aspects of this disease. AIDS is an important precedent, and it is likely that other less pathogenic retroviruses will eventually turn dut to cause some of the rarer immunodeficiency disorders in children and adults. For instance, it has long been suspected that viruses may cause some of the non-familial types of severe combined immunodeficiency in infants; in fact HIV-I infection now has to be considered in the differential diagnosis.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52135056998673,"sku":"NLS9789401070669","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401070669.jpg?v=1757546856"},{"product_id":"immunotherapy-of-disease-book-tj-hamblin-9780746200452","title":"Immunotherapy of Disease","description":"Immunotherapy began in 1774 when the Dorset farmer Benjamin Jesty inoculated his wife and two sons with the pus from the teat of a cow suffering from cow pox, using his wife's knitting needle as a vaccinating implement. It has made slow progress. Meanwhile the science of Immunology has burgeoned so much that if all immunologists read every page of the Journal of Immunology, let alone the other Immunology journals, then they would have no time left to write for it. I am pleased that some of them have found the time to write for this volume. In spite of the rapid expansion in immuno- logical knowledge and the undreamt of complexity of the immune system that has been unravelled, immunologists have remained until recently erudite but therapeutically effete. Indeed anyone purporting to treat disease by immuno- logical methods has been in danger of being labelled a quack or a crackpot. Happily things are changing. The nine chapters of this volume detail nine quite different approaches to manipulating the immune system for therapeutic benefit. All are experimental and they have been attended with greater or lesser degrees of success. In some cases their main effect has been to elucidate the complexity of the problem. On the other hand, there are people alive and well today as a result of these approaches who would otherwise have perished. Immunotherapy is here to stay and it can only get better.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52137243410705,"sku":"NLS9780746200452","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780746200452.jpg?v=1757557379"},{"product_id":"biochemistry-of-inflammation-book-j-whicher-9780792389859","title":"Biochemistry of Inflammation","description":"Our understanding of inflammation has increased rapidly in  recent years, due in large part to the impact of molecular biology and  gene identification and cloning. This book brings together ideas from  a number of different biochemical disciplines which are frequently not  integrated.    The first chapter gives a visual overview of the subject; the  remaining chapters are organized into three themes: the affector  molecules, the regulatory components and the processes of inflammation  itself.    This book is essential reading for the busy physician or pathologist  who wants to be up-to-date with the latest developments in immunology  as they affect the diagnosis and treatment of many conditions.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52139033788689,"sku":"NLS9780792389859","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":53495041261841,"sku":"NIN9780792389859","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792389859.jpg?v=1757566597"},{"product_id":"immunology-of-endocrine-diseases-book-am-mcgregor-9789401083522","title":"Immunology of Endocrine Diseases","description":"Nineteen eighty-six is a most appropriate year in which to be writing about developments in the organ-specific, autoimmune endocrine diseases. It celebrates the publication 30 years ago in 1956 of the classic papers of Roitt and Doniach and their co-workers I , and of Rose and Witebsky2 and Adams 3 and Purves . These three sets of fundamental observations provided the initial building blocks upon which much of what has been established in the field in the last 30 years was built. No publication of this nature on endocrine autoimmune disease can cover every aspect of the subject. I have chosen to highlight the organs (thyroid and pancreeas) which have attracted the most attention, and the areas of work within these fields within which most research effort is currently focused. There are still some gaps; the insulin and TSH receptors are not considered, nor in any detail are the role of cytotoxic mechanisms in mediating gland destruction. Molecular biology will undoubtedly in the next few years clarify once and for all the controversy that surrounds the structure of the TSH receptor and T cell cloning, the role of cell-mediated cytotoxicity. The pathogenetic mechanisms underlying autoimmunity are increasingly well understood and the search for the aetiology has begun.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52141604733201,"sku":"NLS9789401083522","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401083522.jpg?v=1757577728"},{"product_id":"immunology-of-sexually-transmitted-diseases-book-dj-wright-9789401070577","title":"Immunology of Sexually Transmitted Diseases","description":"9. Wright, D. J. M. (1980). Reaction following treatment of murine borreliosis and Shwartzman type reaction with borrelial sonicates. Parasite Immunol. , 2, 201-21 10. Tekli. l, B. , Habte-Michal, A. , White, N. J. , Warrell, D. A. and Wright, D. J. M. (1983). Meptazinol diminishes the Jarisch-Herxheimer reaction. Lancet, 1, 835-9 II. Wright, D. J. M. (1973). The significance of the fluorescent treponemal antibody (FTA- ABS) test in collagen disorders and leprosy. J. Clin. Pathol. , 26, 968-72 12. Noguchi, H. (1911). A cutaneous reaction in syphilis. J. Exp. Med. , 14, 557-68 13. Frei W. (1925). Eine neue hautreaktion bei 'lymphogranuloma inguinale'. Klin. Wochenschr. , 4, 2148-9 14. Murray, J. F. , Felton, C. P. , Garay, S. M. et al. (1984). Pulmonary complications of the acquired immunodeficiency syndrome. Report of a National Heart, Lung and Blood Institute workshop. N. Engl. J. Med. , 310, 1682-8 15. Ehrmann, S. (1907). Versuche uber autoinfektion bei syphilis. Verh. Dtsch. Dermatol. Gesel Berl. , 1,265-70 16. Gluck, A. , cited by Grin E. 1. (1953). Epidemiology and control of endemic syphilis: report on mass treatment campaign in Bosnia. Monograph I I, pp. 34-5. (Geneva: WHO) 17. Neisser, A. , cited by Chesney, A. (1926). Immunity in syphilis. Medicine (BaIt. ), 5,463-87 18. Grimble, A. and Lessof, M. H. (1965). Anti-prostate antibodies in arthritis. Brit. Med. J. , 11, 263-4 xiii 1 Syphilis S. J.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52141728334097,"sku":"NLS9789401070577","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401070577.jpg?v=1757577988"},{"product_id":"clinical-transplantation-book-gr-catto-9789401079440","title":"Clinical Transplantation","description":"This volume has been written specifically for the practising clinician. All aspects of clinical transplantation have expanded enormously in recent years, but many of the doctors involved have received little or no tuition in immunology as medical students. The various chapters, written by physicians, surgeons, pathologists and immunologists present many of the currently important issues in transplantation and demonstrate that a basic undertaking of immunology is now essential in many areas of clinical practice. Perhaps this book will not only produce an increasing awareness of immunological technique but also and, more importantly, stimulate an abiding interest in this clinically relevant topic. Graeme R. Catto Aberdeen Royal Infirmary vii Series Editor's Note The modern clinician is expected to be the fount of all wisdom concerning conventional diagnosis and management relevant to his sphere of practice. In addition, he or she has the daunting task of comprehending and keeping pace with advances in basic science relevant to the pathogenesis of disease and ways in which these processes can be regulated or prevented. Immunology has grown from the era of antitoxins and serum sickness to a state where the study of many diverse cells and molecules has become integrated into a coherent scientific discipline with major implications for many common and crippling diseases prevalent throughout the world.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52141778469137,"sku":"NLS9789401079440","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401079440.jpg?v=1757578247"},{"product_id":"recent-developments-in-prophylactic-immunization-book-francis-j-zucker-9789401069694","title":"Recent Developments in Prophylactic Immunization","description":"It has been said that never in the history of human progress has a better and cheaper method of preventing illness been developed than immunization. This is well illustrated by the WHO Expanded Programme on Immunization (EPI) which in developing countries is now preventing nearly a million deaths annually from measles, pertussis and neonatal tetanus, and for which there is a commitment by the WHO and UNICEF to protect all children by immunization by the end of the decade. This enormous undertaking will be facilitated by the rapid advances in molecular biology and recombinant DNA technology, in the understanding of immunological mechanisms and by the production and application of monoclonal antibodies so that the structure and location of important antigenic determinants or epitopes can be determined. Chemical synthesis of oligopeptides has been simplified, and computer programmes and X-ray crystallography provide the tools for the determination of three-dimensional structure of proteins, so that the structure and location of important antigenic determinants or epitopes can be predicted. These techniques have opened the way to the improvement of existing vaccines and to the development and production of new vaccines against infections for which vaccines are not available. New vaccines under development include vaccines against hepatitis B, hepatitis A, malaria, vaccines for typhoid, cholera, rota virus infection and other diarrhoeal diseases, leprosy, rabies, the acquired immune deficiency syndrome (AIDS), rubella, EB virus, schistosomiasis and other infections. These recent developments are discussed in the volume by internationally recognized experts assembled from several countries.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52141808386321,"sku":"NLS9789401069694","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401069694.jpg?v=1757578299"},{"product_id":"phagocytes-and-disease-book-ms-klempner-9789401070683","title":"Phagocytes and Disease","description":null,"brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52142408663313,"sku":"NLS9789401070683","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401070683.jpg?v=1757580015"},{"product_id":"immunological-aspects-of-oral-diseases-book-l-ivanyi-9789401083508","title":"Immunological Aspects of Oral Diseases","description":null,"brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52142471938321,"sku":"NLS9789401083508","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401083508.jpg?v=1757580318"},{"product_id":"immunology-of-ent-disorders-book-glenis-k-scadding-9789401046299","title":"Immunology of ENT Disorders","description":"Until recently, the contribution of immunological knowledge to the under- standingand management ofENTdisorders was slight, being largely confined to the appreciation that many rhinitic patients were allergic. Happily, this situation is rapidly changing: the immunological basis of many disorders of the ears, nose and throat is becoming recognized and the mechanisms of the reactions involved are being elucidated. From this, rational therapy should evolve. This book aims to highlight some of the areas in which immunological mechanisms are involved in otorhinolaryngology. It is written by experts in their respective fields of immunology and allergy, otology, rhinology and pathology. It opens with an overview ofthe pathways ofthe immune response and the cells and molecules involved, leading to an appreciation of the normal defence mechanisms of the upper respiratory tract and possible areas offailure. There is then a chapter on HIV infection and how this may present to otorhinolaryngologists. The normal function of the tonsil and the immunological effects oftonsillectomy are then considered. The varying roles of fungi in ENT disorders ranging from commensal through allergen to invasive organisms is assessed by Professor R. J. Hay. Perhaps the most obvious immunological contribution to management thus far lies in the immunocytochemical diagnosis of pathological conditions of the ears, nose and throat and this is covered in a chapter by Professor Leslie Michaels.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52142487306513,"sku":"NLS9789401046299","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401046299.jpg?v=1757580438"},{"product_id":"immunology-of-liver-disease-book-hc-thomas-9789401046251","title":"Immunology of Liver Disease","description":"The role of the immune response in both the pathology of liver disease and in the modulation ofliver injury has been the subject of intense research. This book aims to present the current understanding of the involvement of the immune response in liver disease. The first chapters examine the role of the immune response in viral infections of the liver. These viruses cause hepatitis of varying severity and it is thought that many of the mechanisms responsible for liver cell injury are immunologically mediated. In addition three of these viruses, hepatitic B, C, and D, are associated with persistent infection and chronic liver disease. The role of the immune response in viral persistence is discussed. Further chapters are devoted to the three major autoimmune liver diseases which are thought to be the result of loss of tolerance to autologous liver tissue. There has been much recent research on cellular immune responses in these diseases but knowledge of the immunological processes which lead to the breakdown of tolerance and the mechanisms of tissue damage are limited. Other research has concentrated on the identification of the antigens which are the targets of this immune response. Linkage disequilibrium between MHC alleles and autoimmune diseases has suggested a role for immunogenetic factors.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52142898282769,"sku":"NLS9789401046251","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401046251.jpg?v=1757581861"},{"product_id":"immunology-of-malignant-diseases-book-vs-byers-9789401079457","title":"Immunology of Malignant Diseases","description":"A central issue in tumour immunology is whether human tumours express antigens which can be termed tumour-specific. Robins in the introductory chapter in which the expression of antigens in human tumours is compared with that in experimentally induced animal tumours.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52143696412945,"sku":"NLS9789401079457","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401079457.jpg?v=1757585578"},{"product_id":"immunological-aspects-of-gastroenterology-book-yr-mahida-9780792370710","title":"Immunological Aspects of Gastroenterology","description":"Diseases of the gastrointestinal tract are common. There is  increasing appreciation of the importance of the immune system in the  pathogenesis of a number of these diseases. This book covers basic  aspects of innate and adaptive immunity in the gastrointestinal tract,  oral tolerance, and cellular and molecular mechanisms of acute and  chronic inflammation. Specific disease covered include bacterial  infections, human immunodeficiency virus (HIV) infection, coeliac  disease, and inflammatory bowel disease. Other topics include mucosal  immunisation and intestinal transplantation immunology.    The readership of this book includes clinicians, scientists, and  students interested in the gastrointestinal tract.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52143891120401,"sku":"NLS9780792370710","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":53552070721809,"sku":"NIN9780792370710","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792370710.jpg?v=1757586449"},{"product_id":"immunotherapy-of-disease-book-tj-hamblin-9789401073226","title":"Immunotherapy of Disease","description":"Immunotherapy began in 1774 when the Dorset farmer Benjamin Jesty inoculated his wife and two sons with the pus from the teat of a cow suffering from cow pox, using his wife's knitting needle as a vaccinating implement. It has made slow progress. Meanwhile the science of Immunology has burgeoned so much that if all immunologists read every page of the Journal of Immunology, let alone the other Immunology journals, then they would have no time left to write for it. I am pleased that some of them have found the time to write for this volume. In spite of the rapid expansion in immuno- logical knowledge and the undreamt of complexity of the immune system that has been unravelled, immunologists have remained until recently erudite but therapeutically effete. Indeed anyone purporting to treat disease by immuno- logical methods has been in danger of being labelled a quack or a crackpot. Happily things are changing. The nine chapters of this volume detail nine quite different approaches to manipulating the immune system for therapeutic benefit. All are experimental and they have been attended with greater or lesser degrees of success. In some cases their main effect has been to elucidate the complexity of the problem. On the other hand, there are people alive and well today as a result of these approaches who would otherwise have perished. Immunotherapy is here to stay and it can only get better.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52144326541585,"sku":"NLS9789401073226","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401073226.jpg?v=1757588400"},{"product_id":"immunology-of-eye-diseases-book-s-lightman-9789401076234","title":"Immunology of Eye Diseases","description":"The eye can become involved in immune-mediated diseases that affect it alone or as part of a multi-organ disease process. Much immunological attention has been focused on other organs affected by these processes and the subject of the immunology of eye diseases is a relatively new one. Many of these diseases that involve the eye are not life-threatening but can result in devastat- ing loss of sight that if bilateral, will have major effects on the patient's life. Systemic immunological investigations are generally unhelpful in these patients and one of the major problems in this field has been the lack of diseased tissue available for examination to determine the pathological processes involved. Our poor understanding of basic mechanisms of disease in the eye has meant that treatment of many of these conditions is often inadequate. It has become possible to apply in the eye many ofthe techniques used to investigate the role of the immune system in other systems. Animal models of many of the disease processes have also allowed dissection of the immune response both within and outside the eye. It is my belief that a greater understanding of the mechanisms by which the structures in the eye become damaged will allow more specific and effective therapeutic strategies to be devised.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52144914301201,"sku":"NLS9789401076234","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401076234.jpg?v=1757591161"},{"product_id":"immunology-of-ent-disorders-book-glenis-k-scadding-9780792389149","title":"Immunology of ENT Disorders","description":"Until recently, the contribution of immunological knowledge to the under- standingand management ofENTdisorders was slight, being largely confined to the appreciation that many rhinitic patients were allergic. 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The varying roles of fungi in ENT disorders ranging from commensal through allergen to invasive organisms is assessed by Professor R. J. Hay. Perhaps the most obvious immunological contribution to management thus far lies in the immunocytochemical diagnosis of pathological conditions of the ears, nose and throat and this is covered in a chapter by Professor Leslie Michaels.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52147235782929,"sku":"NLS9780792389149","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792389149.jpg?v=1757599871"},{"product_id":"complement-in-health-and-disease-book-k-whaley-9789401049818","title":"Complement in Health and Disease","description":"Since the first edition of Complement in Health and Disease was published in 1986, significant advances have been made. The cDNAs for all of the components and some of the receptors have been cloned and sequenced. The chromosomal localization and the structural organization of a number of these genes have now been determined. These advances are now facilitating research into the structure of the complement proteins, the nature of the complement deficiency syndromes, the regulation of complement gene expression and the role of complement in different diseases. This edition contains contributions from both basic and clinical scientists in a format which we hope will appeal to both immunologists and physicians who wish to know more about this fascinating and important host defence system. The introductory chapter by John Weiler presents a historical background to research on the complement system and describes the biochemical events occurring during activation of the system. In Chapter 2 Alastair Dodds and Tony Day discuss the phylogeny and evolution of the complement system. 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Whereas traditionally, only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increasedthe number ofapproved agents, resulting in numerous trials to further evaluate their potential. In addition, products of the biotechnology industry, - monoclonal antibodies, cytokines, cytokine antagonists and other products of genetic engineering that target key molecular pathways in disease pathogenesis, have either already made, or are on the verge of making an important impact on treat- ment. There is also considerable interest in the potential ofcell-based thera- pies (particularly hematopoietic stem and dendritic celltherapy) ofallo-and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. Gene therapy offers considerable promise for suppressing pathogenic processes in either transplantation or autoimmune disorders. The possibility of combining these important new advances to maximize benefit to the patient, and to minimize possible untoward effects (that are also given extensive coverage in this book)is one ofthe most exciting challenges ofcontemporary medicine. This volume is intended both forpracticing physicians and surgeons and for biomedical scientists at the graduate\/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppres- sion, and to provide state-of-the-artreviews ofcurrent developments in each area. 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The information in this book is easily accessible and should  be helpful for researchers and clinical specialists as a convenient  overview of the field, as well as a comprehensive introduction for  students starting in this area of research.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52409859506449,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52409860194577,"sku":"NLS9789401061063","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401061063.jpg?v=1758776097"},{"product_id":"immunology-of-sexually-transmitted-diseases-book-dj-wright-9780746200872","title":"Immunology of Sexually Transmitted Diseases","description":"9. Wright, D. J. M. (1980). Reaction following treatment of murine borreliosis and Shwartzman type reaction with borrelial sonicates. Parasite Immunol., 2, 201-21 10. Tekli. l, B., Habte-Michal, A., White, N. J., Warrell, D. A. and Wright, D. J. M. (1983). Meptazinol diminishes the Jarisch-Herxheimer reaction. Lancet, 1, 835-9 I. Wright, D. J. M. (1973). The significance of the fluorescent treponemal antibody (FTA- ABS) test in collagen disorders and leprosy. J. Clin. Pathol., 26, 968-72 12. Noguchi, H. (1911). A cutaneous reaction in syphilis. J. Exp. Med., 14, 557-68 13. Frei W. (1925). Eine neue hautreaktion bei 'lymphogranuloma inguinale'. Klin. Wochenschr., 4, 2148-9 14. Murray, J. F., Felton, C. P., Garay, S. M. et al. (1984). Pulmonary complications of the acquired immunodeficiency syndrome. Report of a National Heart, Lung and Blood Institute workshop. N. Engl. J. Med., 310, 1682-8 15. Ehrmann, S. (1907). Versuche uber autoinfektion bei syphilis. Verh. Dtsch. Dermatol. Gesel Berl., 1,265-70 16. Gluck, A., cited by Grin E. 1. (1953). Epidemiology and control of endemic syphilis: report on mass treatment campaign in Bosnia. Monograph I I, pp. 34-5. (Geneva: WHO) 17. Neisser, A., cited by Chesney, A. (1926). Immunity in syphilis. Medicine (BaIt. ), 5,463-87 18. Grimble, A. and Lessof, M. H. (1965). Anti-prostate antibodies in arthritis. Brit. Med. J., 11, 263-4 xiii 1 Syphilis S. J.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52422785630481,"sku":"NLS9780746200872","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":53499310113041,"sku":"NIN9780746200872","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780746200872.jpg?v=1759149052"},{"product_id":"aids-pathogenesis-book-h-schuitemaker-9780792361961","title":"AIDS Pathogenesis","description":"Infection with the human immunodeficiency virus is  characterized by the destruction of the host immune system as also  reflected by a progressive loss of CD4-positive T-cells. 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Finally, the book discusses the currently used laboratory markers that  allow for monitoring of the clinical course of infection.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52425874374929,"sku":"NLS9780792361961","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":53360179446033,"sku":"NIN9780792361961","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792361961.jpg?v=1759156049"},{"product_id":"immunology-of-the-connective-tissue-diseases-book-g-s-panayi-9780792389880","title":"Immunology of the Connective Tissue Diseases","description":"Connective tissue diseases demand study because of their  frequency, morbidity and mortality. They present intriguing challenges  in the fields of diagnosis, management and research. 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The book is aimed at physicians interested in understanding the  immunological basis of these diseases, and at immunologists who are  either entering this field for the first time and would like to have a  convenient state-of-the-art account of its status, or who are  researching in one area and would like to acquaint themselves with the  developments which have taken place in others.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52425911599377,"sku":"NLS9780792389880","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792389880.jpg?v=1759156150"},{"product_id":"immunology-of-eye-diseases-book-s-lightman-9780792389088","title":"Immunology of Eye Diseases","description":"The eye can become involved in immune-mediated diseases that affect it alone or as part of a multi-organ disease process. 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Basic background on the immune apparatus in the intestine is also  discussed, as are the effects of inflammation on intestinal  permeability.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52428492472593,"sku":"NLS9789401053235","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789401053235.jpg?v=1759164308"},{"product_id":"immunology-of-renal-disease-book-cd-pusey-9789401057387","title":"Immunology of Renal Disease","description":"Although it has been appreciated for many years that immune processes underlie most types of glomerulonephritis, it is the recent explosion in knowl- edge of cellular and molecular immunology that has prompted another book on the subject. The understanding of the mechanisms involved in renal injury requires the integration of information from in vitro cell-culture systems, experimental models of disease, and clinical studies. This volume draws on all of these sources in an attempt to explain current concepts of nephritis. Increased emphasis is placed on autoimmune processes, as opposed to the deposition of circulating immune complexes, although it will be apparent that these may overlap in the area of in situ immune complex formation. Of central importance in autoimmunity is the relationship between antigen pre- senting cells (including B cells) expressing MHC class I molecules, autoan- tigenic peptides, T helper lymphocytes, and various effector cells. 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An effective functioning of these molecules requires  interaction with immune cells. Receptors for antibodies, Fc receptors,  provide this critical link between the humoral and cellular branches  of the immune system. This book presents a comprehensive overview of  the different Fc receptors currently recognized. The first part of the  book contains state-of-the-art overviews on the biological role of  FcR. The latest information on FcR heterogeneity, FcR physiology,  FcR-ligand recognition, their crucial coordinating role in immunity,  interactions with other immunoreceptors, and the role of FcR in  immunoglobulin transport and catabolism are discussed. The clinical  importance of FcR is developed in the second part of the book. The  well-recognized roles of FcR in allergy, inflammation, infectious  diseases, autoimmune disorders, and immunotherapeutic importance are  reviewed. The information in this book is easily accessible and should  be helpful for researchers and clinical specialists as a convenient  overview of the field, as well as a comprehensive introduction for  students starting in this area of research.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52429778485521,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52429779206417,"sku":"NLS9780792350217","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792350217.jpg?v=1759167868"},{"product_id":"cancer-immunology-book-ra-robins-9789048157143","title":"Cancer Immunology","description":"CYTOTOXIC T LYMPHOCYTES-INDUCTION AND ACTIVATION . . . . . . . . . . . . . . . . . . 124 EPSTEIN BAR VIRUS ASOCIATED TUMOURS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 Immunoblastic lymphomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126 Burkitt's lymphoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127 NPC and Hodgkin's lymphoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 127 Vaccines for EBV associated malignancies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 128 HUMAN PAPILOMA VIRUS (HPV) ASOCIATED TUMOURS . . . . . . . . . . . . . . . . . . . . . . . . . 129 T cell responses against HPV . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 Cytotoxic T cell responses in HPV infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 Vaccines and clinical trials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132 Recombinant viral vaccines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132 Peptide vaccines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133 Bacterial fusion protein vaccines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134 Potential Pitfalls for CTL based immunotherapy of CaCX . . . . . . . . . . . . . 134 PROSPECTS FOR OTHER VIRAL Y ASOCIATED CANCERS . . . . . . . . . . . . . . . . . . . . . . . . . 135 Hepatitis viruses and primary liver cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 135 Human herpes virus 8 and Kaposi's sarcoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 Human T lymphotropic virus and adult T cell leukaemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 136 Emerging tumour viruses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 CONCLUDING REMARKS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 ACKNOWLEDGEMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138 REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139 Chapter 8 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52477937451281,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52477938434321,"sku":"NLS9789048157143","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789048157143.jpg?v=1759846395"},{"product_id":"aids-pathogenesis-book-h-schuitemaker-9789048154074","title":"AIDS Pathogenesis","description":"Infection with the human immunodeficiency virus is  characterized by the destruction of the host immune system as also  reflected by a progressive loss of CD4-positive T-cells. This finally  results in the host's incapacity to deal with opportunistic infections  and the immune surveillance of tumors, a clinical status known as the  Acquired Immunodeficiency Syndrome (AIDS).    The book AIDS Pathogenesis provides the reader with a complete  overview of the clinical course of HIV-1 infection. It describes the  clinical aspects of primary infection, the different clinical outcomes  of HIV-1 infection, and strategies for anti-viral treatment. In  addition, more fundamental aspects of HIV-1 infection are reviewed.  These include the biology of the virus and the novel insights in AIDS  pathogenesis. Not only is the significance of an HIV-specific cellular  and humoral immune response discussed, but also the possible  incapacity of the adult human host to deal with T-cell destruction.  Finally, the book discusses the currently used laboratory markers that  allow for monitoring of the clinical course of infection.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52481554579729,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52481556087057,"sku":"NLS9789048154074","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789048154074.jpg?v=1759851897"},{"product_id":"immunology-of-gastrointestinal-disease-book-tt-macdonald-9780792389613","title":"Immunology of Gastrointestinal Disease","description":"Gastrointestinal diseases present a considerable problem in  human medicine in terms of both morbidity and mortality. The aim of  this book is to cover the different immunological disorders of the gut  with special reference to immunopathological and protective  mechanisms. It will be of general interest to clinicians, scientists  and students concerned with the gastrointestinal tract.    Topics covered include: the current status of research into  toxin-secreting pathogens, Campylobacter, Giardia and HIV; the  immunological features of idiopathic inflammatory gut diseases such as  Crohn's disease and intractable diarrhoea; the genesis of the flat  mucosa; the iatrogenic diseases of the gut such as graft-versus-host  disease and small bowel allografts; the immune mechanisms and lesions  in the gut of patients with parasitic nematode infections (very  important in the tropics).    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It bridges the divide between basic immunological research and clinical practice.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52675694526737,"sku":"NLS9780792389682","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792389682.jpg?v=1762302493"},{"product_id":"immunology-of-neuromuscular-disease-book-reinhard-hohlfeld-9789401046220","title":"Immunology of Neuromuscular Disease","description":"The neuromuscular diseases comprise the disorders of peripheral nerve, neuromuscular junction, and muscle (Figure 1). This book addresses the immunologically mediated neuromuscular diseases, including Guillain-Barre syndrome and other autoimmune neuropathies, the Lambert-Eaton myas- thenic syndrome, myasthenia gravis, and the autoimmune diseases of muscle. Two chapters are devoted to the vasculitis and human immunodeficiency virus-mediated neuromuscular diseases. The experimental models of neuritis and myasthenia gravis are addressed in separate chapters. An introductory chapter provides a general background to autoimmunity. I wish to thank my contributing colleagues, all of whom are recognized experts in their respective fields, for their willingness to cooperate in this project. Furthermore, I am grateful to Dr Bill Hoffman of Stanford University who generously assisted in the editing of several chapters during his time spent with us on a sabbatical. I am also indebted to the editor and editorial staff of Kluwer Academic Publishers for their help and advice during preparation of this book. 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This volume draws on all of these sources in an attempt to explain current concepts of nephritis. Increased emphasis is placed on autoimmune processes, as opposed to the deposition of circulating immune complexes, although it will be apparent that these may overlap in the area of in situ immune complex formation. Of central importance in autoimmunity is the relationship between antigen pre- senting cells (including B cells) expressing MHC class I molecules, autoan- tigenic peptides, T helper lymphocytes, and various effector cells. The mechanisms by which the immune system may lead to tissue injury are also becoming better understood, and consideration is given to the role of inflam- matory cells, the complement proteins, and soluble factors such as cytokines and eicosanoids.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52687292530961,"sku":"NLS9780792389644","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792389644.jpg?v=1762330106"},{"product_id":"immunology-of-neuromuscular-disease-book-r-hohlfeld-9780792388449","title":"Immunology of Neuromuscular Disease","description":"The neuromuscular diseases comprise the disorders of peripheral nerves, the neuromuscular junction, and muscle. Both pre- and post-synaptic elements of the neuromuscular junction may become targets of autoimmune attack in different diseases. This book addresses the immunologically-mediated neuromuscular diseases, including Guillain-Barre syndrome and other autoimmune neuropathies, the Lambert-Eaton myasthenic syndrome, myasthenia gravis, and the autoimmune diseases of muscle. Two chapters are devoted to the vasculitic and HIV-mediated neuromuscular diseases. The experimental models of neuritis and myasthenia gravis are addressed in separate chapters. An introductory chapter provides a general background to autoimmunity. 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