Epigenetics in Organ Specific Disorders

Epigenetics in Organ Specific Disorders by Chandra S Boosani

**Selected for Doody’s Core Titles® 2024 in Clinical Genetics** Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth. Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies.

Dr. Chandra S. Boosani is an Assistant Professor at the Genetics, Epigenetics & Molecular Biology Lab, within the Department of Translational Research, at the College of Osteopathic Medicine, Pacific Western University School of Health Sciences, CA, U.S.A. His research focuses on developing and testing anticancer proteins, and identifying mechanisms of epigenetic drug action, with emphasis on developing recombinant proteins, drug testing in live mice, and analyzing sequencing data. Dr. Boosani has published in such peer reviewed journals as Seminars in Cancer Biology, Blood, Pharmaceuticals, Gene Regulation and Systems Biology, and Protein Expression and Purification. Ritobrata Goswami is a Assistant Professor in the School of Bioscience, IIT Kharagpur, West Bengal, India.

SKU	Nicht verfügbar
ISBN 13	9780128239315
ISBN 10	012823931X
Titel	Epigenetics in Organ Specific Disorders
Autor	Chandra S Boosani
Serie	Translational Epigenetics
Buchzustand	Nicht verfügbar
Bindungsart	Paperback
Verlag	Elsevier Science Publishing Co Inc
Erscheinungsjahr	2022-12-05
Seitenanzahl	666
Hinweis auf dem Einband	Die Abbildung des Buches dient nur Illustrationszwecken, die tatsächliche Bindung, das Cover und die Auflage können sich davon unterscheiden.