Two-Dimensional DNA Typing by Andre G Uitterlinden

Two-Dimensional DNA Typing by Andre G Uitterlinden

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Zusammenfassung

A critical analysis of a new genome scanning method which is based on a combination of two independent electrophoretic separation principles. Following an introduction to the general methodology, applications of this technique and its future directions are discussed.

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Two-Dimensional DNA Typing by Andre G Uitterlinden

New technology for analyzing complex genomes is an important area of modern molecular biosciences. This book focuses on a recently developed genome scanning method, termed two-dimensional 2-D DNA typing, which is based on a combination of two independent electrophoretic separation principles. When separation according to size is coupled to separation according to base-pair composition, complex genomes can be resolved in a number of DNA fragments. These fragments or subsets can be visualized, for example, by hybridization analysis with specific probes. Genome scanning by 2-D DNA typing finds applications in many areas, such as linkage and association studies for identifying genetic traits in humans, animals and plants, studies on genetic instabilities in cancers, classification studies in bacteria and other lower organisms, studies on human mutation rates, and the identification of mutations in large genes.
SKU Nicht verfügbar
ISBN 13 9780137914500
ISBN 10 0137914504
Titel Two-Dimensional DNA Typing
Autor Andre G Uitterlinden
Buchzustand Nicht verfügbar
Bindungsart Hardback
Verlag Taylor & Francis Ltd
Erscheinungsjahr 1994-03-31
Seitenanzahl 220
Hinweis auf dem Einband Die Abbildung des Buches dient nur Illustrationszwecken, die tatsächliche Bindung, das Cover und die Auflage können sich davon unterscheiden.