The true story of the little-known mental-health pioneer who revolutionised how we see the defining problem of our era: anxiety.

Panic, depression, sorrow, guilt, disgrace, obsession, sleeplessness, low confidence, loneliness, agoraphobia ... Dr Claire Weekes knew how to treat them, but was dismissed as underqualified and overly populist by the psychiatric establishment. In a radical move, she had gone directly to the people. Her international bestseller Self Help for Your Nerves, first published in 1962 and still in print, helped tens of millions of people to overcome all of these, and continues to do so.

Weekes pioneered an anxiety treatment that is now at the cutting edge of modern psychotherapies. Her early explanation of fear, and its effect on the nervous system, is state of the art. Psychologists use her method, neuroscientists study the interaction between different fear circuits in the brain, and many psychiatrists are revisiting the mind-body connection that was the hallmark of her unique work. Face, accept, float, let time pass: hers was the invisible hand that rewrote the therapeutic manual.

This understanding of the biology of fear could not be more contemporary - 'acceptance' is the treatment du jour, and all mental-health professionals explain the phenomenon of fear in the same way she did so many years ago. However, most of them are unaware of the debt they have to a woman whose work has found such a huge public audience. This book is the first to tell that story, and to tell Weekes' own remarkable tale, of how a mistaken diagnosis of tuberculosis led to heart palpitations, beginning her fascinating journey to a practical treatment for anxiety that put power back in the hands of the individual.