{"title":"Sarah Zabel","description":null,"products":[{"product_id":"fighting-chance-book-sarah-zabel-9781735845401","title":"Fighting Chance","description":"\u003cp\u003eWINNER of the IndieReader Discovery Award (Psychology \/ Mental Health)\u003c\/p\u003e\u003cp\u003eSILVER MEDALIST Independent Publisher Book Award (Psychology \/ Mental Health)\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFighting Chance\u003c\/em\u003e approaches its subject with hope. -- \u003cem\u003eForeword\u003c\/em\u003e \u003cem\u003eClarion Reviews\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003eA depressed patient rides his bicycle through the night, returning the next day without his depression. Researchers testing a new anti-tuberculosis drug note that their test subjects - though dying - are inexplicably happy. A PhD student investigating the source of noise in an imaging signal realizes he is seeing a high-level organization of brain function... \u003c\/p\u003e\u003cp\u003e\u003cem\u003eFighting Chance: How Unexpected Observations and Unintended Outcomes Shape the Science and Treatment of Depression \u003c\/em\u003etakes the reader inside the circuitous search for the causes and cures for depression, the leading cause of ill health and disability world-wide. A surprisingly human tale of failed experiments and unanticipated victories, \u003cem\u003eFighting Chance\u003c\/em\u003e reveals many of the people and experiences behind the modern approach to understanding and treating depression. The story begins with the serendipitous discovery of antidepressant medications, an unexpected advance that encouraged psychiatrists to reconceive major depression as an illness rather than an emotional state. The discoveries pile on, showing depression's relationship with stress, inflammation, circadian rhythms, and more. As scientists work to make sense of these observations and advance the biology of depression, they are also learning about vulnerability and resistance, and the process of recovery. \u003c\/p\u003e\u003cp\u003eFrom its underpinnings in cellular neuroscience to current research efforts, \u003cem\u003eFighting Chance\u003c\/em\u003e is a scientific journey inside depression. 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Researchers testing a new anti-tuberculosis drug note that their test subjects - though dying - are inexplicably happy. A PhD student investigating the source of noise in an imaging signal realizes he is seeing a high-level organization of brain function... \u003c\/p\u003e\u003cp\u003e\u003cem\u003eFighting Chance: How Unexpected Observations and Unintended Outcomes Shape the Science and Treatment of Depression \u003c\/em\u003etakes the reader inside the circuitous search for the causes and cures for depression, the leading cause of ill health and disability world-wide. A surprisingly human tale of failed experiments and unanticipated victories, \u003cem\u003eFighting Chance\u003c\/em\u003e reveals many of the people and experiences behind the modern approach to understanding and treating depression. 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