Base Excision Repair Pathway, The: Molecular Mechanisms And Role In Disease Development And Therapeutic Design by David M Wilson Iii

Base Excision Repair Pathway, The: Molecular Mechanisms And Role In Disease Development And Therapeutic Design by David M Wilson Iii

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Zusammenfassung

This book will serve as the preeminent text book on the topic of "base excision repair", a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes.

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Base Excision Repair Pathway, The: Molecular Mechanisms And Role In Disease Development And Therapeutic Design by David M Wilson Iii

This book will serve as the preeminent text book on the topic of 'base excision repair', a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.This book represents one of the most extensive efforts to date to cover the topic of 'base excision repair'. It includes chapters by many of the most established investigators in the field, from all over the world.
SKU Nicht verfügbar
ISBN 13 9789814719728
ISBN 10 9814719722
Titel Base Excision Repair Pathway, The: Molecular Mechanisms And Role In Disease Development And Therapeutic Design
Autor David M Wilson Iii
Buchzustand Nicht verfügbar
Bindungsart Hardback
Verlag World Scientific Publishing Co Pte Ltd
Erscheinungsjahr 2017-02-09
Seitenanzahl 824
Hinweis auf dem Einband Die Abbildung des Buches dient nur Illustrationszwecken, die tatsächliche Bindung, das Cover und die Auflage können sich davon unterscheiden.
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