The Lymphatic System in Health and Disease by J Winny Yun

The Lymphatic System in Health and Disease by J Winny Yun

The lymphatic system develops and functions in parallel with the blood circulatory system (termed the hemovasculature) and accomplishes transport of interstitial fluids, dietary lipids, and reverse transport of cholesterol, immune cells, and antigens--providing a critical homeostatic fluid balance and transmission of immune cells and mediators back to the cardiovascular system. Although the daily flow of lymph (normally 1-2 L/day under unstressed conditions) is far lower than that of daily blood flow (which is 7,500 L/day), without the adequate functioning of the lymphatics, virtually all organs and tissues would acutely suffer many different physical and inflammatory stresses ranging from edema to organ system failure. Although blood and lymphatic vessels often form in anatomic parallels to one another, our knowledge of the workings of the lymphatic system, the fine structure of lymphatic networks, how they function in different organs, and how they are regulated physiologically and immunologically are far from parallel; our knowledge of the lymphatic system still remains at only a tiny fraction of what is understood about the cardiovascular system. Although both the cardiovascular and lymphatic systems are important transport systems, what they transport and how they transport and propel these very different cargoes could not be more dissimilar.

This book provides an overview of the history of the discovery (and re-discovery) of the components of the lymphatic system, lymphatic anatomy, physiological functions of lymphatics, molecular features of the lymphatic system, and clinical perspectives involving lymphatics which may be of interest to scientists, clinicians, patients, and the lay public. We provide a current understanding of some of the more important structural similarities and differences between lymphatics and the blood vascular system, their coordinated control by angiogenic and hemangiogenic growth factors and other modulators, the fate and lineage determinants which control lymphatic development, and the roles that lymphatics may play in several different diseases.

Yun, J. Winny: - J. Winny Yun is a PhD candidate in the Department of Molecular and Cellular Physiology at Louisiana State University Health Sciences Center-Shreveport. She received her BS from Johns Hopkins University in 2012. Her current research project focuses on understanding the roles of lymphatic proteins in brain endothelial cells and their microparticles in health and disease. She has been funded through the Annette Funicello Research Fund for Neurological Research and is a recipient of a fellowship from the Center for Cardiovascular Diseases and Sciences at LSUHSC-S.

SKU	Nicht verfügbar
ISBN 13	9781615047918
ISBN 10	1615047913
Titel	The Lymphatic System in Health and Disease
Autor	J Winny Yun
Serie	Colloquium Series On Integrated Systems Physiology: From Molecule To Function To Disease
Buchzustand	Nicht verfügbar
Bindungsart	Paperback
Verlag	Morgan & Claypool Publishers
Erscheinungsjahr	2018-11-30
Seitenanzahl	89
Hinweis auf dem Einband	Die Abbildung des Buches dient nur Illustrationszwecken, die tatsächliche Bindung, das Cover und die Auflage können sich davon unterscheiden.
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