{"product_id":"my-math-grades-prek-5-dinah-zike-s-teaching-math-science-with-foldables-book-mcgraw-hill-9780021083220","title":"My Math, Grades Prek-5, Dinah Zike's Teaching Math \u0026 Science with Foldables","description":"Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. \u003cp\u003e\u003ci\u003eHot-Melt Extrusion: Pharmaceutical Applications\u003c\/i\u003e covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: \u003c\/p\u003e \u003cul\u003e \u003cli\u003eprinciples and die design of single screw extrusion\u003c\/li\u003e \u003cli\u003etwin screw extrusion techniques and practices in the laboratory and on production scale\u003c\/li\u003e \u003cli\u003eHME developments for the pharmaceutical industry\u003c\/li\u003e \u003cli\u003esolubility parameters for prediction of drug\/polymer miscibility in HME formulations\u003c\/li\u003e \u003cli\u003ethe influence of plasticizers in HME\u003c\/li\u003e \u003cli\u003eapplications of polymethacrylate polymers in HME\u003c\/li\u003e \u003cli\u003eHME of ethylcellulose, hypromellose, and polyethylene oxide\u003c\/li\u003e \u003cli\u003ebioadhesion properties of polymeric films produced by HME\u003c\/li\u003e \u003cli\u003etaste masking using HME\u003c\/li\u003e \u003cli\u003eclinical studies, bioavailability and pharmacokinetics of HME products\u003c\/li\u003e \u003cli\u003einjection moulding and HME processing for pharmaceutical materials\u003c\/li\u003e \u003cli\u003elaminar dispersive \u0026amp; distributive mixing with dissolution and applications to HME\u003c\/li\u003e \u003cli\u003etechnological considerations related to scale-up of HME processes\u003c\/li\u003e \u003cli\u003edevices and implant systems by HME\u003c\/li\u003e \u003cli\u003ean FDA perspective on HME product and process understanding\u003c\/li\u003e \u003cli\u003eimproved process understanding and control of an HME process with near-infrared spectroscopy\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eHot-Melt Extrusion: Pharmaceutical Applications\u003c\/i\u003e is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eThis is the first book from our brand new series \u003ci\u003eAdvances in Pharmaceutical Technology.\u003c\/i\u003e\u003c\/b\u003e \u003cb\u003eFind out more about the series here.\u003c\/b\u003e\u003c\/p\u003e","brand":"WoB","offers":[{"title":"US \/ GOOD \/ SBYB","offer_id":50107226849553,"sku":"CIN0021083223G","price":0.0,"currency_code":"EUR","in_stock":false},{"title":"US \/ VERY_GOOD \/ SBYB","offer_id":51332624515345,"sku":"CIN0021083223VG","price":0.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0021083223.jpg?v=1751355162","url":"https:\/\/www.worldofbooks.com\/de-de\/products\/my-math-grades-prek-5-dinah-zike-s-teaching-math-science-with-foldables-buch-mcgraw-hill-9780021083220","provider":"World of Books ","version":"1.0","type":"link"}