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Distributions and Sobolev spaces.- Operators in Banach spaces.- Examples of boundary value problems.- Semigroups and laplace transform.- Homogenization of second order equations.- Homogenization in elasticity and electromagnetism.- Fluid flow in porous media.- Vibration of mixtures of solids and fluids.- Examples of perturbations for elliptic problems.- The Trotter-Kato theorem and related topics.- Spectral perturbation. Case of isolated eigenvalues.- Perturbation of spectral families and applications to selfadjoint eigenvalue problems.- Stiff problems in constant and varialbe domains.- Averaging and two-scale methods.- Generalities and potential method.- Functional methods.- Scattering problems depending on a parameter.