This Study Guide presents a condensed explanation of the major principles from The Human Brain, 5th Edition. It closely parallels chapter content from the textbook, with topical outlines at the beginning of each chapter. Discussions of major concepts are supplemented by numerous figures and tables, with citations to figures in the text included for easy reference. Self-evaluation questions review specific ideas covered in each chapter, and answers with rationales at the end of the book reinforce the correct information. A comprehensive review exam with many clinical vignette questions focuses on scenarios that illustrate neurobiological concepts in practice. Blank pathway diagrams of neural pathways serve as labeling exercises for further evaluation of anatomical concepts.