Part I: Ontology, Phylogeny, and Tissue Distribution of Mast Cells
1. Paul Ehrich's Mastzellen: A Historical Perspective of Relevant Developments in Mast Cell Biology
Hana Saleh, Harsha Vyas, Emma Peiris, Niva Misra, and Guha Krishnaswamy
2. The Phylogenetic Profile of Mast Cells
Enrico Crivellato , Luciana Travan, and Domenico Ribatti
3. Mast Cell Development and Function in the Zebrafish
Sahar I Da'as, Tugce B. Balci, and Jason N. Berman
4. Human Mast Cell and Basophil/Eosinophil Progenitors
Gail M Gauvreau and Judah A Denburg
5. Methods for the Study of Mast Cell Recruitment and Accumulation in Different Tissues
Tatiana G. Jones and Michael F. Gurish
6. Notch2 Signaling in Mast-cell Development & Distribution in the Intestine
Mamiko Sakata-Yanagimoto and Shigeru Chiba
Part II: Mast Cells in Human Health and Disease7. Mast Cells in Human Health and DiseaseErin J. DeBruin, Matthew Gold, Bernard C. Lo, Kimberly Snyder, Alissa Cait, Nikola Lasic, Martin Lopez, Kelly M. McNagny, and Michael R. Hughes
8. The Emerging Prominence of the Cardiac Mast Cell as a Potent Mediator of Adverse Myocardial Remodeling
Joseph S. Janicki, Gregory L. Brower, and Scott P. Levick
9. The Parasympathetic Nervous System as a Regulator of Mast Cell Function
Paul Forsythe
10. Growth of Human Mast Cells from Bone Marrow and Peripheral Blood-Derived CD34
+ Pluripotent Hematopoietic CellsGeethani Bandara, Dean D. Metcalfe, and Arnold S. Kirshenbaum
11. Isolation and Characterization of Human Intestinal Mast Cells
Axel Lorentz, Gernot Sellge, and Stephan C. Bischoff
12. Human Mast Cell Activation with Viruses and Pathogen Products
Ian Haidl and Jean S. Marshall
Part III: Molecular Mechanisms of Mast Cell Function
13. Basic Techniques to Study FceRI Signaling in Mast Cells
Yuko Kawakami and Toshiaki Kawakami
14. Membrane-cytoskeleton Dynamics in the Course of Mast Cell Activation
Pavel Draber and Petr Draber
15. Fc RI Expression and Dynamics on Mast Cells
Eon J. Rios and Janet Kalesnikoff
16. Regulation of Mast Cell Survival and Apoptosis
Christine Moeller Westerberg, Maria Ekoff and Gunnar Nilsson
17. Protein Tyrosine Phosphatases in Mast Cell Signaling
Alexander Geldman and Catherine J. Pallen
18. MicroRNA Function in Mast Cell Biology:Protocols to Characterize and Modulate microRNA Expression
Steven Maltby, Maximilian Plank, Catherine Ptaschinski, Joerg Mattes, and Paul S. Foster
Part IV: Mast Cell Products and Mediators
19. Assay of Mast Cell Mediators
Madeleine Radinger, Bettina M. Jensen, Emily Swindle, and Alasdair M. Gilfillan
20. Induction Of Mast Cell Apoptosis By A Novel Secretory Granule-Mediated Pathway
Fabio R. Melo, Sara Wernersson, and Gunnar Pejler
21. Measurement of Nitric Oxide in Mast Cells with the Fluorescent Indicator DAF-FM Diacetate
Chris D. St. Laurent, Tae Chul Moon, and A. Dean Befus
22. Real-time Imaging of Ca2+ Mobilization and Degranulation in Mast Cells
Roy Cohen, David A. Holowka, and Barbara A. Baird#
23. Flow Cytometry-based Monitoring of Mast Cell Activation
Glenn Cruse, Alasdair M. Gilfillan, and Daniel Smrz
24. Measurement of Mast Cell Surface Molecules using High-throughput Immunophenotyping using Transcription (HIT)
D. James Haddon, Justin A. Jarrell, Michael R. Hughes, Kimberly Snyder, Kelly M. McNagny, Michael G. Kattah, and Paul J. Utz
Part V: Mouse Models of Disease to Study Mast Cell Function
25. Investigatiotion using Novel Mouse Models of Mast Cell Deficiency and Mast Cell-specific Gene Inactivation
Katrin Peschke, Anne Dudeck, Anja Rabenhorst, Karin Hartmann, and Axel Roers
26. Evaluation of Synovial Mast Cell Functions in Autoimmune Arthritis
Kichul Shin and Peter A. Nigrovic
27. Methods for the Study of Mast Cells in Cancer
Nichole R. Blatner, FuNien Tsai, and Khashayarsha Khazaie
28. Studying Mast Cells in Peripheral Tolerance by using a Skin Transplantation Model
Victor C. de Vries, Isabelle Le Mercier, Elizabeth C. Nowak, and Randolph J. Noelle
29. The Function of Mast Cells in Autoimmune Glomerulonephritis
Renato C. Monteiro, Walid Beghdadi, Lydia Celia Madjene, Maguelonne Pons, Michel Peuchmaur, and Ulrich Blank
30. A Mouse Model of Atopic Dermatitis
Yuko Kawakami and Toshiaki Kawakami
31. Mouse Models of Allergic Asthma
Matthew Gold, David Marsolais, and Marie-Renee Blanchet
32. Methods in Assessment of Airway Reactivity in Mice
Matthew Gold and Marie-Renee Blanchet