This book is intended for students who are starting a serious and detailed study of organic synthesis. It is assumed that they will already have completed a course in elementary organic chemistry which includes the reactions of simple functional groups and basic concepts such as reaction chemistry.
Emphasises the basic principles of the subject. The first ten chapters lay the ground work for carbon-carbon bond formation, functional group transformations, etc. with detailed additions which reflect new work. The remaining chapters on boron, phosphorus and silicon reagents, and selected syntheses have undergone extensive revisions. Chapters on selenium reagents and asymmetric synethesis are new for this edition.
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"...an excellent guide both to reactions which are of importance in synthesis and to the principles underlying the formation of various types of bonds." (Endeavour)
Table of Contents
1. Introduction. 2. Functionalisation and interconversion of functional groups. 3. Formation of carbon-carbon bonds: the principles. 4. Formation of carbon-carbon bonds: reactions of organometallic compounds. 5. Formation of carbon-carbon bonds: the use of stablized carbanions and related nucleophiles. 6. Formation of carbon-heteroatom bonds: the principles. 7. Ring closure (and ring opening). 8. Reduction. 9. Oxidation. 10. Protective groups. 11. Boron reagents. 12. Phosphorous reagents. 13. Silicon reagents. 14. Selenium reagents. 15. Asymmetric synthesis. 16. Selected syntheses.
Guidebook to Organic Synthesis by R. Mackie
Used - Very Good
Pearson Education Limited
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