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Viral Vector Approaches in Neurobiology and Brain Diseases Riccardo Brambilla

Viral Vector Approaches in Neurobiology and Brain Diseases By Riccardo Brambilla

Viral Vector Approaches in Neurobiology and Brain Diseases by Riccardo Brambilla


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Summary

This book covers key aspects related to the use of viral vectors in neurobiology, with a major emphasis on basic mechanisms of synaptic plasticity, learning, and memory, as well as molecular neuropharmacology and experimental animal models of brain diseases.

Viral Vector Approaches in Neurobiology and Brain Diseases Summary

Viral Vector Approaches in Neurobiology and Brain Diseases by Riccardo Brambilla

Aiming toward improvement in the safety, efficiency, and specificity of viral vectors for neurobiological research and clinical applications, Viral Vector Approaches in Neurobiology and Brain Diseases covers key aspects related to the use of viral vectors in neuroscience, with a major emphasis on basic mechanisms of synaptic plasticity, learning, and memory, as well as molecular neuropharmacology and experimental animal models of brain disorders. The volume begins by delving into features of the viral vectors currently available in neuroscience and their production methods, and it then continues onward to examples of successful applications of viral vector technology to psychiatric and memory research, current applications of viral vector technology in the context of neurological disorders, as well as various cutting-edge applications of viral vector technology to neuroscience, including optogenetics. Written for the Neuromethods series, the chapters of this book contain the kind of detailed description and implementation advice that promotes successful, repeatable results.

Practical and up to date, Viral Vector Approaches in Neurobiology and Brain Diseases will be useful not only to neurobiologists wishing to routinely use viral vectors in the laboratory but also to experienced scientists needing detailed new protocols for a variety of experimental applications.

Table of Contents

Part I: Types of Viral Vectors in Neuroscience Research

1. Lentiviral Vectors as Research Tools in Neurobiology: Design and Production

Alessandro Papale and Riccardo Brambilla

2. Recombinant Adenovirus in Neurobiology

Qian Li and Tong-Chuan He

3. Adeno-Associated Virus-Based Vectors

Nathalie Dutheil and Erwan Bezard

4. Herpes Simplex Virus 1 (HSV-1)-Based Vectors

Aldo Pourchet, Matias E. Melendez, Anna Greco, and Alberto L. Epstein

5. Alphavirus-Based Vectors

Kenneth Lundstrom

Part II: Viral Vectors in Memory Research and Psychiatric Diseases

6. Viral Vectors to Study Synaptic Function

Helene Marie

7. Using Viral Vectors to Study the Memory Trace in Mice

Asim J. Rashid, Chen Yan, and Sheena A. Josselyn

8. Development of Cell-Type Specific Viral Vectors to Tease Apart the Neural Circuitry that Contributes to Drug Addiction

Susan M. Ferguson and John F. Neumaier

9. Using Viral-Mediated Gene Transfer to Study Depressive-Like Behavior

Amy R. Furay and John F. Neumaier

Part III: Viral Vectors in Neurological Disorders

10. Gene Therapy for Parkinson's Disease

Erika Elgstrand Wettergren, Luis Quintino, Giuseppe Manfre, and Cecilia Lundberg

11. Lentiviral Vectors in Huntington's Disease Research and Therapy

Aurelie Delzor, Noelle Dufour, and Nicole Deglon

12. Application of Viral Vectors to Motor Neuron Disorders

Elisabeth Dirren and Bernard L. Schneider

Part IV: Applications of Viral Vector Technology to Neuroscience Research

13. In Vivo Gene Silencing by Virally Delivered MicroRNA

Eugenia V. Gurevich, Mohamed R. Ahmed, and Yonatan Carl

14. Viral Manipulation of Neural Stem/Precursor Cells

Nunzio Iraci, Giulia Elisabetta Tyzack, Chiara Cossetti, Clara Alfaro-Cervello, and Stefano Pluchino

15. Viral Vector-Based Techniques for Optogenetic Modulation In Vivo

Mathias Mahn, Shiri Ron, and Ofer Yizhar

16. Viral Vectors for Optogenetics of Hypothalamic Neuropeptides

H. Sophie Knobloch, Alexander Charlet, Ron Stoop, and Valery Grinevich

17. Viral Vectors in Primate Research: Examples from Parkinson's Disease Research

Gregory Porras, Benjamin Dehay, and Erwan Bezard

Additional information

NLS9781493959433
9781493959433
1493959433
Viral Vector Approaches in Neurobiology and Brain Diseases by Riccardo Brambilla
New
Paperback
Humana Press Inc.
2016-08-23
347
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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