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Karch's Pathology of Drug Abuse, Third Edition By Steven B. Karch, MD (Private Consultant, Berkeley, California, USA)

Karch's Pathology of Drug Abuse, Third Edition by Steven B. Karch, MD (Private Consultant, Berkeley, California, USA)

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Summary

A guide to the pathology and pharmacology of commonly abused drugs. It focuses on the investigation of drug-related deaths and on practical approaches in detecting drug abuse. It provides information on the clinical aspects and consequences of drug abuse.

Karch's Pathology of Drug Abuse, Third Edition Summary

Karch's Pathology of Drug Abuse, Third Edition by Steven B. Karch, MD (Private Consultant, Berkeley, California, USA)

AUTHORITATIVE INFORMATION FROM THE SOURCE YOU TRUST

The third edition of Karch's Pathology of Drug Abuse continues to provide a comprehensive yet accessible guide to the pathology, toxicology, and pharmacology of commonly abused drugs. As in previous editions, the focus remains on the investigation of drug-related deaths and on practical approaches to the detection of drug abuse. It covers in detail the clinical consequences of drug usage and provides the latest information on clinical aspects of drug abuse. This well-written, extensively referenced resource supplies a mixture of clinical information and pathology findings.

SEE WHAT'S NEW IN THE THIRD EDITION:

  • New information on methamphetamine abuse
  • New chapter on GHB, ketamine, and select herbal hallucinogens
  • New micrographs showing pathology of drug related deaths
  • Over 1000 new references
  • The mechanism of sudden death in cocaine users and overdose in heroin abusers
  • Toxicology and pathology of ephedrine
  • Neurochemistry of excited delirium
  • Psychotic behavior in stimulant abusers

    About the author: Steven B. Karch has appeared as an expert witness in international cases, including advice to counsel in the Harold Shipman murder trial. He is an assistant medical examiner in San Francisco, where he consults on cases of drug-related deaths. He received his bachelors degree from Brown University, did graduate work in cell biology and biophysics at Stanford, and received his M.D. from Tulane University Medical School.
  • Karch's Pathology of Drug Abuse, Third Edition Reviews

    ABOUT THE THIRD EDITION: "All healthcare practitioners and organizations need this book. I love the organization and detail. Thorough does not do the detail justice. If every pathologist were as dedicated to a task as Dr. Karch has demonstrated in his preparation of the third edition, there would be fewer errors in the forensic aspects of the judicial system. I congratulate Dr. Karch for the best work ever written on drug abuse." - Charles L. Winek, Ph.D. Toxicology Editor, Forensic Science International" a mine of information about the pathology and toxicology of drugs of misuse. It is essential for any healthcare professional involved in the care, clinical management, or autopsy of drug misusers to have a clear understanding of how a particular drug affects the body, short-term and long-term, and what relevance the metabolism of the drug has to its clinical manifestation. This book provides all the answers. Dr. Karch is to be congratulated on producing the best and most readable book I have seen on the subjects included and I recommend it to anyone who works in any way with drug misusers or the investigation of drug related deaths or illness." - Jason Payne-James, Editor, Journal of Forensic Clinical Medicine "Karch's book is well illustrated and extensively referencedI warmly recommend it to anyone who deals in any capacity with the effects of substance misuse." - Chris Milroy, Medico-Legal Centre, Watery Street, Sheffield, UK ABOUT THE SECOND EDITION: "It is easy today for physicians to become technicians rather than professionals. A technician knows how to respond to a problem. The professional has the depth of knowledge that brings real understanding to a problem. This bookpresents a comprehensive view of each subject that it discusses. Dr. Karch's book is a book for professionals." -Journal of Forensic Science ABOUT THE THIRD EDITION "Dr. Karch has produced a truly comprehensive and useful reference work that belongs on the shelf of any professional interested in the sequelae of drug abuse." -Archives of Pathology and Laboratory Medicine

    Table of Contents

    COCAINE
    Incidence
    Epidemiology
    History
    Cultivation and Manufacture
    Drug Constants
    Routes of Ingestion
    Metabolism of Cocaine and Its Metabolites
    Problems of Test Interpretation
    Cocaine Tissue Disposition
    Cocaine's Effects on Catecholamine and the Heart
    External Markers of Cocaine Abuse
    Toxicity by Organ System
    When is Cocaine the Cause of Death?

    OTHER NATURALLY OCCURRING STIMULANTS
    Absinthe
    Caffeine
    Ephedrine
    Khat

    SYNTHETIC STIMULANTS
    Amphetamine and Methamphetamine
    Methylphenidate (Ritalin (TM))
    Phenylpropanolamine
    Fenfluramine

    HALLUCINOGENS
    Phenylethylamine Derivatives
    Substituted Amphetamines (Phenylisopropylamines)
    Phenylalkylamines

    NARCOTICS
    Incidence
    Epidemiology
    Classification of Narcotic Agents
    History of Opiate Abuse
    Cultivation and Manufacture
    Opiate Classification
    Interpretation of Blood and Tissue Concentrations
    Medical Consequences of Opiate Abuse
    Pulmonary Disorders

    DISASSOCIATIVE ANESTHETICS
    Phencyclidine
    Ketamine
    Gamma-hydroxybutyrate (GHB)

    ANABOLIC STEROIDS
    Incidence
    Epidemiology
    History
    Steroid Abuse
    Pharmacology
    Steroid-related Disorders
    Detecting Steroid Abuse

    SOLVENTS
    Incidence
    Epidemiology
    General considerations
    Absorption and tissue disposition
    Clinical syndromes
    Appendix 1: Conversion Formulas
    Appendix 2: Blood Alcohol Concentrations
    Appendix 3: Volume of Distribution Calculations
    Appendix 4: Normal Heart Weights

    Additional information

    GOR010929109
    9780849303432
    0849303435
    Karch's Pathology of Drug Abuse, Third Edition by Steven B. Karch, MD (Private Consultant, Berkeley, California, USA)
    Used - Good
    Hardback
    Taylor & Francis Inc
    2001-12-26
    568
    N/A
    Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
    This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in very good condition, but if you are not entirely satisfied please get in touch with us

    Customer Reviews - Karch's Pathology of Drug Abuse, Third Edition