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In this illuminating book, Dr. Gerald M. Edelman offers a new theory of knowledge based on striking scientific findings about how the brain works. And he addresses the related compelling question: Does the latest research imply that all knowledge can be reduced to scientific description?  Edelman’s brain-based approach to knowledge has rich implications for our understanding of creativity, of the normal and abnormal functioning of the brain, and of the connections among the different ways we have of knowing. While the gulf between science and the humanities and their respective views of the world has seemed enormous in the past, the author shows that their differences can be dissolved by considering their origins in brain functions. 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Scientists and philosophers have pondered these questions for more than two thousand years, but not until now has there been the possibility of answers grounded in scientific experiment. With this book, Edeman and Tononi present an empirically supported full-scale theory of consciousness. The theory provides for the first time a scientific understanding of the most general and fundamental properties of consciousness - the private and unitary nature of experience and yet the infinite variety of conscious states, stretching as widely as one's memory process might explain the generation of this fantastic number of unified conscious states -something far beyond the capabilities of present-day computers? To answer this question, the authors apply all of the resources and insights of modern neuroscience, from the largest computer models of the brain even constructed to new experiments that detect the changes in brain activity that occur when we are conscious or unconscious of a stimulus. Their arguments build on radical ideas earlier introduced by Nobel Laureate Gerald Edelman himself when he first applied Darwinian principles to the development of brain and mind. 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Between them, they examine from different but complementary directions the relationships that connect the higher brain--memory, learning, perception, thinking--with what goes on at the most basic levels of neural activity, with particular stress on the role of local neuronal circuits.Edelman's major hypothesis is that the conscious state results from phasic reentrant signaling occurring in parallel processes that involve associations between stored patterns and current sensory or internal input. This selective process occurs by the polling of degenerate primary repertoires of neuronal groups that are formed during embryogenesis and development. Edelman's theory extrapolates to the brain the selectionistic immunological theories for which he was awarded the 1972 Nobel Prize in Physiology or Medicine. Mountcastle's paper reviews what is known about the actual structure of various parts of the neo cortex. 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If you had a complete copy of a dinosaurs DNA and the genetic code, you still would not be able to make a dinosauror even determine what one looked like. Why? How do animals get their shape and how does shape evolve? In this  important book, Nobel laureate Gerald M. Edelman challenges  the notion that an understanding of the genetic code and of  cell differentiation is sufficient to answer these questions. Rather, he argues, a trio of related issues must also be investigatedthe development of form, the evolution of form, and the morphological and functional bases of behavior. 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How can the disparate domains of mind and body be reconciled? The quest for a scientifically based understanding of consciousness has attracted study and speculation across the ages. In this direct and non-technical discussion of consciousness, Dr. Gerald M. Edelman draws on a lifetime of scientific inquiry into the workings of the brain to formulate answers to the mind-body questions that intrigue every thinking person.\u003cbr\u003eConcise and understandable, the book explains pertinent findings of modern neuroscience and describes how consciousness arises in complex brains. Edelman explores the relation of consciousness to causation, to evolution, to the development of the self, and to the origins of feelings, learning, and memory. 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