Dementia and Motor Neuron Disease by Michael Strong
Amyotrophic lateral sclerosis (ALS)--also termed motor neuron disease or Lou Gehrig's disease--is a common disorder and a number of texts have appeared over the last several years regarding either its clinical or biological characteristics. However, there are no existing texts that discuss the clinical, neuroimaging, neuropathological and neurochemical characteristics of dementia in ALS. This is in spite of the increasing evidence that dementias occur in ALS and that they share many features in common with a frontotemporal lobar degeneration. The importance of this is highlighted by the increasing interest in frontotemporal lobar degeneration as a major cause of dementia in the aging population, in some studies exceeding that of Alzheimer's disease. Moreover, there is a considerable spectrum of cognitive impairment in ALS, with recent estimates suggesting that almost two-thirds of ALS patients will have some degree of frontal cognitive or behavioural impairment. This represents a dramatic shift in our conceptualization of ALS as a purely motor system selective disorder. This text will provide a single authorative reference on the current understanding of frontotemporal dementia in ALS and will find a broad market in the neurosciences field. Because of the crossover between the dementias and motor neuron diseases, this will be applicable to both clinical and research groups focusing on either dementia or ALS. The design of the book and the topics selected will also find broad applicability to neuroimaging and neuropsychology. The intent is to have this as a true reference standard to established clinicians and researchers, as well as graduate students studying neurodegeneration.
Michael J Strong MD FRCPC is Professor and Co-Chair, Department of Clinical Neurological Sciences, University of Western Ontario and Scientist, Cell Biology Research Group, Robarts Research Institute, London, ON, Canada
| SKU | Unavailable |
| ISBN 13 | 9780415391665 |
| ISBN 10 | 0415391660 |
| Title | Dementia and Motor Neuron Disease |
| Author | Michael Strong |
| Condition | Unavailable |
| Binding Type | Hardback |
| Publisher | CRC Press |
| Year published | 2006-07-27 |
| Number of pages | 328 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
| Note | Unavailable |