Modeling and Analysis of Bio-molecular Networks by Pei Wang

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Summary

It first provides an overview of approaches to reconstruct various bio-molecular networks, and then discusses the modeling and dynamical analysis of simple genetic circuits, coupled genetic circuits, middle-sized and large-scale biological networks, clarifying the relationships betweenthe structures, dynamics and functions of the networks covered.

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Modeling and Analysis of Bio-molecular Networks by Pei Wang

This book addresses a number of questions from the perspective of complex systems: How can we quantitatively understand the life phenomena? How can we model life systems as complex bio-molecular networks? Are there any methods to clarify the relationships among the structures, dynamics and functions of bio-molecular networks? How can we statistically analyse large-scale bio-molecular networks?

Focusing on the modeling and analysis of bio-molecular networks, the book presents various sophisticated mathematical and statistical approaches. The life system can be described using various levels of bio-molecular networks, including gene regulatory networks, and protein-protein interaction networks. It first provides an overview of approaches to reconstruct various bio-molecular networks, and then discusses the modeling and dynamical analysis of simple genetic circuits, coupled genetic circuits, middle-sized and large-scale biological networks, clarifying the relationships betweenthe structures, dynamics and functions of the networks covered. In the context of large-scale bio-molecular networks, it introduces a number of statistical methods for exploring important bioinformatics applications, including the identification of significant bio-molecules for network medicine and genetic engineering. Lastly, the book describes various state-of-art statistical methods for analysing omics data generated by high-throughput sequencing.

This book is a valuable resource for readers interested in applying systems biology, dynamical systems or complex networks to explore the truth of nature.

“The book is built as a much-needed bridge between a life-sciences perspective and mathematical/computational modellingThe book is addressed to a wide audience, being written in an accessible style, middle-way between a textbook and a collection of state-of-the-art reviews. … The authors succeed at creating a much-needed resource that responds, with the appropriate amount of information, to current needs.” (Irina Ioana Mohorian, zbMATH 1522.92001, 2023)
Dr. Liu Shu-Tang is a professor of College of Control Science and Engineering, Shandong University. His research areas include Spatial chaotic theory of nonlinear dynamical systems and its application, Qualitative theory and qualitative control of complex system, Control and applications of fractals.
Dr. Wang Pei is a teacher of College of Electrical Engineering and Automation, Qilu University of Technology. Her research areas include Nonlinear dynamical systems, Control and applications of fractals.(For internal use only)
SKU Unavailable
ISBN 13 9789811591433
ISBN 10 9811591431
Title Modeling and Analysis of Bio-molecular Networks
Author Pei Wang
Condition Unavailable
Binding Type Hardback
Publisher Springer Verlag, Singapore
Year published 2020-12-07
Number of pages 464
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.