{"title":"Gale Rhodes","description":null,"products":[{"product_id":"crystallography-made-crystal-clear-book-gale-rhodes-9780125870733","title":"Crystallography Made Crystal Clear","description":"Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field.  Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. Rhodes' personal CMCC Home Page also provides access to tools and links to resources discussed in the text. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers. This updated and expanded new edition uses attractive four-color art, web tool access for further study, and concise language to explain the basis of X-ray crystallography, increasingly vital in today's research labs.","brand":"WoB","offers":[{"title":"GB \/ GOOD \/ INTERNAL","offer_id":49542949077265,"sku":"GOR008461266","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ GOOD \/ SBYB","offer_id":50485342470417,"sku":"CIN0125870736G","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ LIKE_NEW \/ INTERNAL","offer_id":50535582105873,"sku":"GOR011813046","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ VERY_GOOD \/ SBYB","offer_id":51612279996689,"sku":"CIN0125870736VG","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ VERY_GOOD \/ INTERNAL","offer_id":52830068015377,"sku":"GOR009235402","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0125870736.jpg?v=1751290204"},{"product_id":"crystallography-made-crystal-clear-book-gale-rhodes-9780125870726","title":"Crystallography Made Crystal Clear","description":"Macromolecules are the proteins and nucleic acids upon which life depends. Understanding the action of biological macromolecules (giant molecules) requires detailed knowledge of their structures. Most of the more than ten thousand known structures of protein and nucleic acids were obtained by x-ray crystallography, the standard mechanism for determining protein structure. Essentially, proteins are frozen into rigid crystals, which can be stacked up in a repeating pattern--like supermarket displays. The structure of each individual crystal can be determined by the way x-rays are bent when they pass through the composite crystal. Protein structure is essential when investigating protein interactions and planning drug development. \"Crystallography Made Crystal Clear, Second Edition\" explains how scientists discover the structures of the macromolecules. Scientists do not see these molecules directly. Instead, they build models as a means of interpreting data from x-ray diffraction by crystals, or by irradiation by other forms of energy. Users of these models need to know how they are obtained in order to know what they are seeing when they study a model of a macromolecule. They also need to know how to judge whether conclusions they draw from the molecular models are really supported by the models. This book uses visual and geometric models to help readers understand the mathematics that forms the basis of x-ray crystallography. The field of protein crystallography is growing every day and has been instrumental in discovering the molecular principles of biology and in discovering new drugs, such as the recent protease inhibitors for AIDS. The field includes the largest percentage of Nobel prizes than any other scientific discipline. Every major university and drug company has a protein crystallography laboratory and this book is an invaluable aid to those wishing to practice protein crystallography or just learn more about how it is actually done. It provides clear, understandable descriptions of principles of X-ray crystallography. It leads reader through unintimidating and thorough explanations of the underlying mathematics. It provides abundant illustrations, including diagrams, charts, photographs, color stereo, and images. It explains how to read crystallography papers in research journals. It includes brief descriptions of other diffraction methods (neutron, electron, Laue) and the kinds. It is of structural information they can provide. It introduces other methods of macromolecular structure determination (NMR spectroscopy and homology modeling), and provides guidance in judging the quality of these models.","brand":"WoB","offers":[{"title":"US \/ GOOD \/ SBYB","offer_id":50045311484177,"sku":"CIN0125870728G","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ WELL_READ \/ SBYB","offer_id":50344132641041,"sku":"CIN0125870728A","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ VERY_GOOD \/ SBYB","offer_id":52965140136209,"sku":"CIN0125870728VG","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0125870728.jpg?v=1750876875"},{"product_id":"crystallography-made-crystal-clear-book-gale-rhodes-9780125870757","title":"Crystallography Made Crystal Clear","description":"With the advent of recombinant DNA techniques, an increasing number of proteins are being expressed in sufficient quantities to be crystallized for X-ray diffraction analysis. At the same time, the efficient handling of data required to analyze diffraction data from macromolecules and graphics capabilities to display structures obtained from this analysis are also advancing. Consequently, huge numbers of new macromolecular models, especially protein models derived from X-ray crystallographic analysis, have appeared in recent years. The understanding of how crystallographers obtain these protein structures is essential for intelligent use of crystallographic models, whether that use is studying molecular action and interaction in cell structure, trying to unlock the secrets of protein folding, exploring the possibilities of engineering new protein functions, or interpreting results of chemical, kinetic, thermodynamic or spectroscopic experiments on proteins. Most biochemistry or protein texts that address this issue, tend to contain a brief section or chapter on protein crystallography, and often these sections are too cursory and mystifying to provide readers with an incisive and comprehensive account of this specialized topic. At the other end of the spectrum are in-depth treatises that contain a thorough analysis of the theoretical and experimental details useful to practitioners, but often intimidating to non-crystallographers. This book is designed to meet a need for an X-ray analysis that is between brief textbook sections and complete treatment. It should provide non-crystallographers with an explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts should foster wise use of the models, including the recognition of the strengths and weaknesses of pictures and computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells, and carry out most biologically important tasks, this book should interest most biologists. Features of the book include an explanation of the mathematics behind X-ray crystallography and accessible descriptions of principles built on simple foundations.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51265407779089,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ GOOD \/ SBYB","offer_id":52825890357521,"sku":"CIN0125870752G","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0125870752.jpg?v=1751100830"}],"url":"https:\/\/www.worldofbooks.com\/en-gb\/collections\/author-books-by-gale-rhodes.oembed","provider":"World of Books ","version":"1.0","type":"link"}