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Das hat naturlich auch zu man chen Anderungen del' klassischen Methoden del' percutanen Strahlentherapie mit Rontgenstrahlen gefUhrt. Ganz neue Applikationsformen sind, namentlich im Rahmen del' Nuclearmedizin, hinzugekommen. In den Grundlagen jeder Strahlentherapie sind einerseits Physik und Technik sowie Biologie, medizinisches Grundwissen und klinische Erfahrung und andererseits Theorie und Empirie in sehr komplexer Weise miteinander verknupft. Aus diesem Zusammen- wirken haben sich die allgemeinen Methoden del' Strahlentherapie entwickelt. Ihrer Be- sprechung ist Band XVI dieses Handbuches gewidmet, wahrend die speziellen physika- lisch-technischen und strahlenbiologischen Probleme in den Banden I bzw. II dargelegt sind und die Bande XVII-XIX die spezielle Strahlentherapie und damit auch die vor- wiegend klinischen Fragen behandeln. Fur die Abhandlung del' einzelnen Methoden del' Strahlenapplikation konnten Autoren gewonnen werden, die jeweils uber besondere Erfahrungen auf dem zu besprechenden Gebiet verfugen und von denen einige sogar die Grundlagen del' betreffenden Methode geschaffen haben. Zur Begrundung solcher Verfahren mussen naturlich auch grund- satzliche Fragen angeschnitten werden. 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