{"title":"José M Álvarez-Castro","description":null,"products":[{"product_id":"genes-environments-and-interactions-book-jos-lvarezcastro-9783031411588","title":"Genes, Environments and Interactions","description":"\u003cp\u003eGenetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date.\u003c\/p\u003e\n\n\u003cp\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eThe theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci\u003c\/li\u003e\n\u003cli\u003eArbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for\u003c\/li\u003e\n\u003cli\u003eBoth effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out\u003c\/li\u003e\n\u003cli\u003ePopulations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associationsbetween\/among genes and environments)\u003c\/li\u003e\n\u003cli\u003eAll developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003c\/p\u003e\n\n\n\n\n\n\n\n\n\n\u003cp\u003eIn brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish.\u003c\/p\u003e\n\n\u003cp\u003eAll relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51060259717393,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51060262830353,"sku":"NIN9783031411588","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52618583736593,"sku":"NLS9783031411588","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/3031411587.jpg?v=1786614215"}],"url":"https:\/\/www.worldofbooks.com\/en-gb\/collections\/author-books-by-jos-m-lvarez-castro.oembed","provider":"World of Books ","version":"1.0","type":"link"}