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Readers are assumed to have undergraduate-level linear algebra and basic real analysis, while prior exposure to graduate-level probability is recommended. 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It covers essential topics in linear algebra, calculus and optimization, and probability and statistics, demonstrating their relevance in the context of data analysis. Key application topics include clustering, regression, classification, dimensionality reduction, network analysis, and neural networks. What sets this text apart is its focus on hands-on learning. Each chapter combines mathematical insights with practical examples, using Python to implement algorithms and solve problems. Self-assessment quizzes, warm-up exercises and theoretical problems foster both mathematical understanding and computational skills. 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