{"title":"Shabir Ahmad Ganai","description":null,"products":[{"product_id":"natural-hdac-inhibitors-for-epigenetic-combating-of-cancer-progression-book-shabir-ahmad-ganai-9781032279862","title":"Natural HDAC Inhibitors for Epigenetic Combating of Cancer Progression","description":"Natural HDAC Inhibitors for Epigenetic Combating of Cancer Progression deals only with HDAC inhibitors from natural origins including bacteria, fungi, marine organisms and, notably, from diverse plant sources. This book is unique in the sense that it is the only book that discusses wholly and solely HDAC inhibitors of natural origin in the context of cancer chemotherapy. Another peculiar feature of this book is that it debates futuristic nanotechnology approaches for escalating the aqueous solubility, cancer cell uptake, bioavailability and other favourable pharmacological parameters, including the cytotoxicity of natural HDAC inhibitors against cancer cells.   The major features of this book encompass         General compendium of HDAC inhibitors with deep emphasis on the toxicity issues of synthetic HDAC inhibitors      Various groups of natural HDAC inhibitors, their representatives and premier sources      Cyclic tetrapeptides of natural origin and their importance as cancer chemotherapeutic agents      Hydroxamates and depsipeptides from natural sources and their promising role in cancer therapy       Natural flavonoids, their HDAC inhibitory tendency and marvellous anticancer activity      Non-flavonoid natural HDAC inhibitors and their pleasing cytotoxic effects towards cancer models      Combined therapy involving natural flavonoids with other anticancer molecules for synergistic and additive benefits against cancer models      Non-flavonoid HDAC inhibitors and conventional drugs in collaborative mode against aggressive malignancies      Nanotechnology-based delivery of natural HDAC inhibitors for greater therapeutic efficacy over traditional combinatorial therapy  This book is highly beneficial to university professors and research scholars working on epigenetic therapeutics in general, and natural HDAC inhibitors in particular. This book is equally important to medical oncologists, biochemistry as well as pharmacy candidates and students of master's and undergraduate level with a desire to do a doctorate on HDACs, natural HDAC inhibitors, HDAC inhibitor (natural)-based combinatorial chemotherapy and delivery of these inhibitors selectively to tumour sites through revolutionary nanotechnological tactics.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ GARDNERS","offer_id":50698564403473,"sku":"NGR9781032279862","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ NEW \/ INGRAM","offer_id":51115252941073,"sku":"NIN9781032279862","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52586711482641,"sku":"NLS9781032279862","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1032279869.jpg?v=1751238049"},{"product_id":"histone-deacetylase-inhibitors-in-combinatorial-anticancer-therapy-book-shabir-ahmad-ganai-9789811581786","title":"Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy","description":"This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy. HDAC inhibitors are emerging as promising anticancer drug molecules that promote growth arrest, differentiation and apoptosis of cancer cells with tumor selective toxicity.    The book begins with an overview of various epigenetic modifying enzymes that are involved in cancer transition and progression; before exploring the potential of HDACs in cancer treatment. It provides a classification of HDAC inhibitors based on their structural attributes, and addresses HDAC-induced cytotoxicity..    Lastly, it discusses and assesses the rationale behind therapies that combine HDAC inhibitors with other anticancer agents to treat solid tumors. Given its scope, it offers a valuable resource for all researchers, clinicians, and students working in formulation, drug discovery, oncology, and personalized medicine.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52137894674705,"sku":"NLS9789811581786","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789811581786.jpg?v=1757559748"},{"product_id":"histone-deacetylase-inhibitors-in-combinatorial-anticancer-therapy-book-shabir-ahmad-ganai-9789811581816","title":"Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy","description":"This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy. HDAC inhibitors are emerging as promising anticancer drug molecules that promote growth arrest, differentiation and apoptosis of cancer cells with tumor selective toxicity.    The book begins with an overview of various epigenetic modifying enzymes that are involved in cancer transition and progression; before exploring the potential of HDACs in cancer treatment. It provides a classification of HDAC inhibitors based on their structural attributes, and addresses HDAC-induced cytotoxicity..    Lastly, it discusses and assesses the rationale behind therapies that combine HDAC inhibitors with other anticancer agents to treat solid tumors. Given its scope, it offers a valuable resource for all researchers, clinicians, and students working in formulation, drug discovery, oncology, and personalized medicine.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52140016238865,"sku":"NLS9789811581816","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9789811581816.jpg?v=1757572216"}],"url":"https:\/\/www.worldofbooks.com\/en-gb\/collections\/author-books-by-shabir-ahmad-ganai.oembed","provider":"World of Books ","version":"1.0","type":"link"}