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What is unique about this approach and these materials is the idea of narrowing the focus of instruction to seven communicative functions, all of which appear in every chapter from the very first day of the course. 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Based on the most current research, the editor lined up a team of worldwide experts to cover the most exciting research in the area, considering the impact through the human life span.\u003c\/p\u003e \u003cp\u003eThis book is structured in two parts that provide a good balance of foundational and applied content. Part I deals with an overview of mitochondrial dysfunction and its role in the aging process, including metabolic diseases, neuro-affective and neurodegenerative disorders, sepsis, and toxicological aspects. Part I covers therapeutic substance delivery to mitochondria with a focus on cancer, neurodegenerative diseases, and increasing the bioavailability of natural compounds of interest. Several nanoscale strategies are described.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eMitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine\u003c\/i\u003e is a complete resource for researchers in this exciting field. Its comprehensive coverage makes this book particularly interesting to bioscience researchers looking to understand the foundations of mitochondrial health throughout the human life span. 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Metas achieves this goal by essentially doubling the amount of material in each of the six main chapters of Punto y aparte (originally designed as a fourth-semester book), and then by dividing each of these expanded chapters (now called Unidades in Metas) into two self-contained sections (Capítulo A and Capítulo B) to make the amount of material more manageable. Thus, Metas offers the same 12-unit structure found in most intermediate Spanish textbooks (6 units x 2 chapters each = 12 manageable chapters).  In terms of grammar, Metas focuses on key grammatical structures (los puntos clave) critical to the seven communicative functions or goals (las siete metas comunicativas) that are central to intermediate-level study. The seven communicative functions are:    Description (Descripción) Comparison (Comparación) Reactions and recommendations (Reacciones y recomendaciones) Narrating in the past (Narración en el pasado) Talking about preferences (Hablar de los gustos) Hypothesizing (Hacer hipótesis) Talking about the future (Hablar del futuro)     By organizing the text around key grammatical structures, Metas retains the framework of Punto y aparte, resulting in a logical and manageable progression. Additionally, the continual reinforcement and recycling of all seven communicative functions offer students many opportunities to communicate, produce, and create with the language, rather than to simply review the scope and sequence of Spanish grammar of their first-year course.","brand":"WoB","offers":[{"title":"US \/ WELL_READ \/ SBYB","offer_id":50343743750417,"sku":"CIN0073513202A","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ GOOD \/ SBYB","offer_id":50343753810193,"sku":"CIN0073513202G","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ VERY_GOOD \/ SBYB","offer_id":51440935797009,"sku":"CIN0073513202VG","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0073513202.jpg?v=1750972691"},{"product_id":"punto-y-aparte-student-edition-book-sharon-foerster-9780077350215","title":"Punto y Aparte Student Edition","description":null,"brand":"WoB","offers":[{"title":"US \/ GOOD \/ SBYB","offer_id":50343830978833,"sku":"CIN0077350219G","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0077350219.jpg?v=1751227003"},{"product_id":"punto-y-aparte-book-sharon-foerster-9781259602962","title":"Punto y aparte","description":"Punto y aparte uniquely synthesizes the lessons learned in first-year Spanish by focusing on seven core communicative functions (called out with icons throughout the program) and the grammatical structures that support them.  These functions are constantly recycled throughout the program to reflect the real-life use of language.  Grammar review may be found at the back of the program, reserving the main chapters for setting up engaging real-world uses of language and rich cultural presentation.  Punto y aparte offers meaningful communicative practice through writing and speaking activities that help put students on a successful path to progress from simple utterances to more extensive discourse, and from sentence-level to paragraph length expression.","brand":"WoB","offers":[{"title":"US \/ WELL_READ \/ SBYB","offer_id":50412616909073,"sku":"CIN1259602966A","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ VERY_GOOD \/ SBYB","offer_id":50963138314513,"sku":"CIN1259602966VG","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ GOOD \/ SBYB","offer_id":51416815239441,"sku":"CIN1259602966G","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1259602966.jpg?v=1751050466"},{"product_id":"punto-y-aparte-book-sharon-foerster-9780078037054","title":"Punto y aparte","description":"Punto y aparte: Spanish in Review, Moving Toward Fluency  places communicative goals at the forefront of the intermediate Spanish course so students don't just learn about the language, they learn how to use the language in an authentic and natural way that allows students to express themselves with increasing fluency and accuracy in real-world settings.  The proven qualities of Punto y aparte include:   - a focus on seven core communicative functions (called out with icons throughout the program) and the grammatical structures that support them. These functions are constantly recycled throughout the program to reflect the real-life use of language. - meaningful communicative practice through writing and speaking activities presented in a real-world context. In Connect, our composition and peer editing tools along with our Blackboard IM and VoiceBoard tools allow students the opportunity to have communicative practice with their peers outside the classroom as well. Connect is the only integrated learning system that empowers students by continuously adapting to deliver precisely what they need, when they need it, and how they need it, so that your class time is more engaging and effective.   - constant recycling of grammar and vocabulary throughout the program using the seven communicative functions, Para repasar boxes, Pruebas diagnósticas, and the LearnSmart suite of tools. - cultural content in the form of new ¡Cuéntennos! videos and the ¡Viaje conmigo a… videos as well as  readings on art, music and history serve to recycle grammar and vocabulary and to enrich students' experience of language learning and provide a window into Spanish-speaking cultures.  These features support the core goals of the intermediate Spanish course and put students on a successful path from simple utterances to more extensive discourse, from sentence-level to paragraph length expression.*Connect Spanish, including but not limited to the workbook\/lab manual, LearnSmart, the video program, and chat tools, is sold separately and does not come automatically with the purchase of the textbook.","brand":"WoB","offers":[{"title":"US \/ VERY_GOOD \/ SBYB","offer_id":50492277948689,"sku":"CIN0078037050VG","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ WELL_READ \/ SBYB","offer_id":50571063066897,"sku":"CIN0078037050A","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"US \/ GOOD \/ SBYB","offer_id":50719411503377,"sku":"CIN0078037050G","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0078037050.jpg?v=1750843288"},{"product_id":"supplementary-materials-to-accompany-puntos-book-sharon-foerster-9780078040009","title":"Supplementary Materials to Accompany Puntos","description":"Supplementary Materials to accompany Puntos de partida, 8e,  by Sharon Foerster and Jean Miller (University of Texas, Austin) is comprised of worksheets and a teacher's guide. 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