{"title":"Naranjan S Dhalla","description":null,"products":[{"product_id":"pathophysiology-of-heart-failure-book-naranjan-s-dhalla-9780792335719","title":"Pathophysiology of Heart Failure","description":"Pathophysiology of Heart Failure brings together leading  basic scientists and clinicians, presenting new approaches to this  complex problem, involving cardiomyopathic processes and ischemia  perfusion injury. The result is a synthesis of state-of-the-art  information on molecular biology, cellular physiology and  structure-function relationships in the cardiovascular system.  The role which excess intracellular calcium plays in the genesis of  cardiac dysfunction is described as a fundamental mechanism underlying  heart failure; one which may lead to improved prevention and  treatment.    Audience: Clinical and experimental cardiologists will find the  book a helpful source of ideas and inspiration.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51007185256721,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51007187648785,"sku":"NIN9780792335719","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52584004714769,"sku":"NLS9780792335719","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/0792335716.jpg?v=1751395192"},{"product_id":"pathophysiology-of-cardiovascular-disease-book-naranjan-s-dhalla-9781402074523","title":"Pathophysiology of Cardiovascular Disease","description":"Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions.  This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51024518349073,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51024520839441,"sku":"NIN9781402074523","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52673435599121,"sku":"NLS9781402074523","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1402074522.jpg?v=1750793730"},{"product_id":"angiotensin-ii-receptor-blockade-physiological-and-clinical-implications-book-naranjan-s-dhalla-9781461376316","title":"Angiotensin II Receptor Blockade Physiological and Clinical Implications","description":"The relationship between angiotensin II and hypertension was established in 1898 when angiotensin II was shown to modulate systemic blood pressure. Over the intervening decades, a complete characterization of the renin-angiotensin system (RAS) has been achieved, and our understanding of its biochemistry and physiology has led to the directed development of agents such ·as ACE inhibitors and receptor antagonists capable of controlling hypertension. More recently, it was shown that angiotensin II is secreted within certain tissues and that these tissue-specific systems operate independently of the systemic RAS. The novel concept that angiotensin II regulates a number of cardiovascular processes that are unrelated to blood pressure has renewed the interest of both basic and clinical scientists in angiotensin II. The association between angiotensin II and cardiac growth, in particular, has indicated that therapies currently in use for hypertension may have direct application to the treatment of heart failure. The Manitoba Cardiovascular Forum on Angiotensin Receptor Blockade in Winnipeg was convened October 18-20, 1996 to examine the clinical and basic aspects of angiotensin receptor biology as they apply to hypertension and heart failure. In addition, the potential treatment of these conditions using specific angio­ tensin receptor antagonists was addressed within the context of their immediate therapeutic application and future potential.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51027596312849,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51027598868753,"sku":"NIN9781461376316","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52337535418641,"sku":"NLS9781461376316","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1461376319.jpg?v=1754488158"},{"product_id":"heart-function-and-metabolism-book-naranjan-s-dhalla-9781461292203","title":"Heart Function and Metabolism","description":"Proceedings of the Symposium held at the 8th Annual Meeting  of the American Section of the International Society for Heart  Research, July 8-11, 1986, Winnipeg, Canada","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52126812537105,"sku":"NLS9781461292203","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52953458245905,"sku":"NIN9781461292203","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461292203.jpg?v=1757480308"},{"product_id":"pathophysiology-of-heart-disease-book-naranjan-s-dhalla-9780898388640","title":"Pathophysiology of Heart Disease","description":"This point was eloquently made by Dr. Arnold Katz in his Presidential Address (Chapter 1) at the 8th Annual Meeting of the American Section of the International Society for Heart Research held in Winnipeg, Canada, July 8-11, 1986.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52129526186257,"sku":"NLS9780898388640","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780898388640.jpg?v=1757496606"},{"product_id":"pathophysiology-and-pharmacology-of-heart-disease-book-naranjan-s-dhalla-9781461288893","title":"Pathophysiology and Pharmacology of Heart Disease","description":"Proceedings of the Symposium held at Chandigarh, India,  February 1988","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52141375979793,"sku":"NLS9781461288893","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461288893.jpg?v=1757577047"},{"product_id":"heart-hypertrophy-and-failure-book-naranjan-s-dhalla-9781461285267","title":"Heart Hypertrophy and Failure","description":"Heart Hypertrophy and Failure brings together leading  basic scientists and clinicians, presenting improved knowledge of the  pathophysiology and treatment of the condition. The result is a  synthesis of state-of-the-art information on molecular biology,  cellular physiology and structure-function relationships in the  cardiovascular system in health and disease. The papers presented  describe fundamental mechanisms underlying changes in the cellular  machinery during the development of cardiac hypertrophy and heart  failure.    Audience: Students, scientists, clinical and experimental  cardiologists who seek to understand and manage the perplexing  problems of hypertrophy and heart failure.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52141753532689,"sku":"NLS9781461285267","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461285267.jpg?v=1757578113"},{"product_id":"angiotensin-ii-receptor-blockade-physiological-and-clinical-implications-book-naranjan-s-dhalla-9780792381471","title":"Angiotensin II Receptor Blockade Physiological and Clinical Implications","description":"The relationship between angiotensin I and hypertension was established in 1898 when angiotensin I was shown to modulate systemic blood pressure. Over the intervening decades, a complete characterization of the renin-angiotensin system (RAS) has been achieved, and our understanding of its biochemistry and physiology has led to the directed development of agents such -as ACE inhibitors and receptor antagonists capable of controlling hypertension. More recently, it was shown that angiotensin I is secreted within certain tissues and that these tissue-specific systems operate independently of the systemic RAS. The novel concept that angiotensin I regulates a number of cardiovascular processes that are unrelated to blood pressure has renewed the interest of both basic and clinical scientists in angiotensin I. The association between angiotensin I and cardiac growth, in particular, has indicated that therapies currently in use for hypertension may have direct application to the treatment of heart failure. The Manitoba Cardiovascular Forum on Angiotensin Receptor Blockade in Winnipeg was convened October 18-20, 1996 to examine the clinical and basic aspects of angiotensin receptor biology as they apply to hypertension and heart failure. In addition, the potential treatment of these conditions using specific angio- tensin receptor antagonists was addressed within the context of their immediate therapeutic application and future potential.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52327422722321,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52327423279377,"sku":"NLS9780792381471","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792381471.jpg?v=1758062445"},{"product_id":"signal-transduction-and-cardiac-hypertrophy-book-naranjan-s-dhalla-9781461350323","title":"Signal Transduction and Cardiac Hypertrophy","description":"Cellular signaling in cardiac muscle refers to the myriad of stimuli and responses that direct and control the physiological operation of this organ. In response to a chronic increase in workload, cardiac muscle cells can dramatically increase in size to face their increasing contractile demands.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52337391567121,"sku":"NLS9781461350323","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52953457033489,"sku":"NIN9781461350323","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461350323.jpg?v=1758166499"},{"product_id":"signal-transduction-and-cardiac-hypertrophy-book-naranjan-s-dhalla-9781402072185","title":"Signal Transduction and Cardiac Hypertrophy","description":"Cellular signaling in cardiac muscle refers to the myriad of stimuli and responses that direct and control the physiological operation of this organ. In response to a chronic increase in workload, cardiac muscle cells can dramatically increase in size to face their increasing contractile demands.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52340908917009,"sku":"NLS9781402072185","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781402072185.jpg?v=1758171187"},{"product_id":"myocardial-ischemia-book-naranjan-s-dhalla-9781461292210","title":"Myocardial Ischemia","description":"Proceedings of a Satellite Symposium of the XXX International  Physiological Congress, July 8-11, 1986, Winnipeg, Canada","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52455116931345,"sku":"NLS9781461292210","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461292210.jpg?v=1759373277"},{"product_id":"heart-function-and-metabolism-book-naranjan-s-dhalla-9780898388657","title":"Heart Function and Metabolism","description":"Proceedings of the Symposium held at the 8th Annual Meeting  of the American Section of the International Society for Heart  Research, July 8-11, 1986, Winnipeg, Canada","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52476654977297,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52476655763729,"sku":"NLS9780898388657","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780898388657.jpg?v=1759844401"},{"product_id":"pathophysiology-and-pharmacology-of-heart-disease-book-naranjan-s-dhalla-9780792303671","title":"Pathophysiology and Pharmacology of Heart Disease","description":"Research at the molecular and the cellular level has greatly enhanced our understanding of the pathogenesis and management of heart disease. These included the National Academy of Medical Sciences, Indian Council of Medical Research, Council of Scientific and Industrial Research and Department of Science and Technology.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52483059581201,"sku":"NLS9780792303671","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52740051304721,"sku":"NIN9780792303671","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792303671.jpg?v=1759854147"},{"product_id":"role-of-proteases-in-cellular-dysfunction-book-naranjan-s-dhalla-9781493946341","title":"Role of Proteases in Cellular Dysfunction","description":"It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52587728109841,"sku":"NLS9781493946341","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781493946341.jpg?v=1761056864"},{"product_id":"pathophysiology-of-heart-failure-book-naranjan-s-dhalla-9781461285250","title":"Pathophysiology of Heart Failure","description":"Pathophysiology of Heart Failure brings together leading  basic scientists and clinicians, presenting new approaches to this  complex problem, involving cardiomyopathic processes and ischemia  perfusion injury. The result is a synthesis of state-of-the-art  information on molecular biology, cellular physiology and  structure-function relationships in the cardiovascular system.  The role which excess intracellular calcium plays in the genesis of  cardiac dysfunction is described as a fundamental mechanism underlying  heart failure; one which may lead to improved prevention and  treatment.    Audience: Clinical and experimental cardiologists will find the  book a helpful source of ideas and inspiration.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52617234284817,"sku":"NLS9781461285250","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461285250.jpg?v=1761529675"},{"product_id":"renin-angiotensin-system-in-cardiovascular-disease-book-naranjan-s-dhalla-9783031149542","title":"The Renin Angiotensin System in Cardiovascular Disease","description":"This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number onecause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52620278661393,"sku":"NLS9783031149542","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9783031149542.jpg?v=1761538328"},{"product_id":"molecular-defects-in-cardiovascular-disease-book-naranjan-s-dhalla-9781493941155","title":"Molecular Defects in Cardiovascular Disease","description":"Molecular Defects in Cardiovascular Disease provides an in-depth discussion of the molecular mechanisms underlying the genesis of cardiovascular defects and the implications this has on current and emerging targeted therapeutics.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52650401464593,"sku":"NLS9781493941155","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781493941155.jpg?v=1762127872"},{"product_id":"myocardial-ischemia-and-preconditioning-book-naranjan-s-dhalla-9781402071959","title":"Myocardial Ischemia and Preconditioning","description":"Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger\/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52662869459217,"sku":"NLS9781402071959","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781402071959.jpg?v=1762270555"},{"product_id":"heart-hypertrophy-and-failure-book-naranjan-s-dhalla-9780792335726","title":"Heart Hypertrophy and Failure","description":"Heart Hypertrophy and Failure brings together leading  basic scientists and clinicians, presenting improved knowledge of the  pathophysiology and treatment of the condition. The result is a  synthesis of state-of-the-art information on molecular biology,  cellular physiology and structure-function relationships in the  cardiovascular system in health and disease. The papers presented  describe fundamental mechanisms underlying changes in the cellular  machinery during the development of cardiac hypertrophy and heart  failure.    Audience: Students, scientists, clinical and experimental  cardiologists who seek to understand and manage the perplexing  problems of hypertrophy and heart failure.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52662982050065,"sku":"NLS9780792335726","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780792335726.jpg?v=1762270839"},{"product_id":"role-of-proteases-in-cellular-dysfunction-book-naranjan-s-dhalla-9781461490982","title":"Role of Proteases in Cellular Dysfunction","description":"It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors. However, when the activity of proteases is not regulated appropriately, disease processes can result, as seen in Alzheimer’s disease, cancer metastasis and tumor progression, inflammation and atherosclerosis. Thus it is evident that there is an absolute need for a tighter control of proteolytic activities in different cells and tissues.  Aimed at graduate students and researchers with an interest in cellular proteolytic events, Role of Proteases in Cellular Dysfunctions is the second book on Proteases in this series. The book consists of three parts in specified topics based on current literatures for a better understanding for the readers with respect to their subject-wise interests. The first section of this book covers a brief idea about the neuronal disorders and the involvement of proteases such as calpains, caspases and matrix metalloproteases (MMPs). The second section covers the deadly disease cancer and its relation to ubiquitin-proteasome system, MMPs and serine proteases. The last section is about the role of proteases such as calpains, MMPs and serine protease as well as urokinase type plasminogen activator receptor (uPAR) in causing cardiovascular defects.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52663001678097,"sku":"NLS9781461490982","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461490982.jpg?v=1762270886"},{"product_id":"frontiers-in-cardiovascular-health-book-naranjan-s-dhalla-9781402074516","title":"Frontiers in Cardiovascular Health","description":"The Frontiers in Cardiovascular Health varies between and within nations, depend­ ing upon the level at which the battle is fought for better cardiovascular health. According to the 1997 World Health Report, 15 million deaths (i. e. 30% of the total number of deaths) were attributable to cardiovascular diseases and this number is on the rise. The projection for the year 2020 is quite alarming with an expected cardiovascular mortality reaching 50 million. Much of this burden is projected to occur in developing countries, more specifically in the most populous countries of the world, namely China and India. These countries are already burdened with infectious and parasitic diseases and are trying to eradicate such diseases. With increasing life expectancies people all over the world, especially in developing coun­ tries, are exposed to degenerative atherosclerosis resulting in increased cardiovascu­ lar mortality and morbidity. In developing countries, resources available for health care are very limited. For example many of the African countries spend less than $10 per person per year on his\/her entire health care let alone cardiovascular health. The average health care budget for nearly two thirds of the global population is well below $100 per year, on a per capita basis. Therefore, in developing countries health promotion and primary prevention are the frontiers by necessity. Improving awareness and health education is not only a matter of choice but is an absolute necessity.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52675587703057,"sku":"NLS9781402074516","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781402074516.jpg?v=1762302251"},{"product_id":"pathophysiology-of-cardiovascular-disease-book-naranjan-s-dhalla-9781461350842","title":"Pathophysiology of Cardiovascular Disease","description":"Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions.  This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52676029415697,"sku":"NLS9781461350842","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52953457295633,"sku":"NIN9781461350842","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461350842.jpg?v=1762303312"},{"product_id":"frontiers-in-cardiovascular-health-book-naranjan-s-dhalla-9781461350859","title":"Frontiers in Cardiovascular Health","description":"The Frontiers in Cardiovascular Health varies between and within nations, depend­ ing upon the level at which the battle is fought for better cardiovascular health. According to the 1997 World Health Report, 15 million deaths (i. e. 30% of the total number of deaths) were attributable to cardiovascular diseases and this number is on the rise. The projection for the year 2020 is quite alarming with an expected cardiovascular mortality reaching 50 million. Much of this burden is projected to occur in developing countries, more specifically in the most populous countries of the world, namely China and India. These countries are already burdened with infectious and parasitic diseases and are trying to eradicate such diseases. With increasing life expectancies people all over the world, especially in developing coun­ tries, are exposed to degenerative atherosclerosis resulting in increased cardiovascu­ lar mortality and morbidity. In developing countries, resources available for health care are very limited. For example many of the African countries spend less than $10 per person per year on his\/her entire health care let alone cardiovascular health. The average health care budget for nearly two thirds of the global population is well below $100 per year, on a per capita basis. Therefore, in developing countries health promotion and primary prevention are the frontiers by necessity. Improving awareness and health education is not only a matter of choice but is an absolute necessity.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52676087415057,"sku":"NLS9781461350859","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52953457426705,"sku":"NIN9781461350859","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461350859.jpg?v=1762303445"},{"product_id":"myocardial-ischemia-and-preconditioning-book-naranjan-s-dhalla-9781461350361","title":"Myocardial Ischemia and Preconditioning","description":"Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52677738692881,"sku":"NLS9781461350361","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461350361.jpg?v=1762306596"},{"product_id":"molecular-defects-in-cardiovascular-disease-book-naranjan-s-dhalla-9781441971296","title":"Molecular Defects in Cardiovascular Disease","description":"Molecular Defects in Cardiovascular Disease provides an in-depth discussion of the molecular mechanisms underlying the genesis of cardiovascular defects and the implications this has on current and emerging targeted therapeutics.  Divided into three sections, this book covers the scientific foundations of our present understanding as well as the array of clinical manifestations and their treatment.  The first section covers Molecular Mechanisms of Heart Disease, with discussion of the development of cardiovascular dysfunction.  The remaining two sections provide a more clinical focus.  The second, Cardiac Hypertrophy and Heart Failure deals with metabolic derangements, Ca2+ handling, and subcellular remodeling.  It illustrates the wide variety of molecular defects which may serve as targets associated with the transition from cardiac hypertrophy to advanced heart failure.  The third section, Hypertension and Diabetes, provides molecular rationale for the pathogenesis of hypertension and diabetic cardiomyopathy, as well as highlighting the importance of hormones toward this end.   A necessary resource for clinicians and researchers, this book elucidates the experimental basis of the practice of cardiology.  It is the culmination of our advances in the understanding of cardiovascular molecular biology and a blueprint for the efficacious use of targeted therapies.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52678350799121,"sku":"NLS9781441971296","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781441971296.jpg?v=1762307908"}],"url":"https:\/\/www.worldofbooks.com\/en-ie\/collections\/author-books-by-naranjan-s-dhalla.oembed?page=2","provider":"World of Books ","version":"1.0","type":"link"}