{"title":"Biological Magnetic Resonance","description":null,"products":[{"product_id":"carbohydrates-and-nucleic-acids-book-lawrence-j-berliner-9781475794762","title":"Carbohydrates and Nucleic Acids","description":"In the past ten years or so, biological magnetic resonance (NMR and ESR) has fully blossomed and become highly branched. In the 1970s and earlier, a practitioner in biological magnetic resonance was using virtually all of the available methods suitable for his research, with the latter covering a diverse range of systems. Today, the focus of an individual laboratory is actually much narrower, with respect to both the methods and the systems investigated. Thus, those who investigate protein structure by multi­ dimensional NMR spectroscopy do not usually engage in studies involving in vivo spectroscopy. The conferences on biological magnetic resonance now have parallel sessions rather than the single, common session of earlier days. Moreover, topical meetings are becoming more frequent. Therefore, this and future volumes of our series will also focus on specific topical areas. We are proud to present Volume 10 of our series. It focuses on Carbohydrates and Nucleic Acids. In an extensive chapter, Kamerling and Vliegenthart use oligosaccharide-alditols released from mucin-type- glycoproteins to illustrate the power of proton NMR spectroscopy in the determination of carbohydrate structure. Wemmer gives a detailed coverage of the arsenal of modern NMR methods now available for structural studies of nucleic acids. Forthcoming volumes will focus on In Vivo Spectroscopy and Protein Structure. As always, we are anxious to get feedback from the readers and hear their comments and suggestions. Lawrence J.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51231097061649,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51231097782545,"sku":"NIN9781475794762","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52142500479249,"sku":"NLS9781475794762","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1475794762.jpg?v=1750827422"},{"product_id":"in-vivo-spectroscopy-book-lawrence-j-berliner-9781475794793","title":"In Vivo Spectroscopy","description":"In vivo nuclear magnetic and electron spin resonance spectroscopy is concerned, inter alia, with the noninvasive observation of metabolic changes in living systems, including animals and humans. Typically, the physiologi­ cal (or pathological) state of an organ or tissue is monitored. This multi­ faceted approach was developed during the 1980s. It is still a research technique, but will undoubtedly become a clinical tool. We are proud to present this volume (the eleventh of our series) in which some of the pioneers in this area summarize their contributions and review related literature. Bolinger and Lenkinski describe a variety of localization methods suitable for clinical applications of NMR spectroscopy. Schleich, Caines, and Rydzewski summarize their contributions to approaches involving off-resonance rotating frame relaxation and critically compare these with other NMR techniques that may yield similar information. Chang and James outline their approach and share their experience with the technical aspects 1 31 of H and P NMR spectroscopy and spatially localized spectroscopy in studies of brain ischemia. Sodium plays an important role in living systems, a key aspect being the large gradient between intra- and extracellular concentrations of sodium that is maintained by a variety of transport mechanisms. Miller and Elgavish give us a comprehensive review of an important research tool in this 23 area- Na NMR spectroscopy as aided by shift reagents.","brand":"WoB","offers":[{"title":"- \/ - \/ -","offer_id":51231124455697,"sku":"","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":51231125209361,"sku":"NIN9781475794793","price":0.0,"currency_code":"GBP","in_stock":false},{"title":"GB \/ NEW \/ INGRAM","offer_id":52409913704721,"sku":"NLS9781475794793","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/1475794797.jpg?v=1751053003"},{"product_id":"spin-labeling-book-lawrence-j-berliner-9781461280606","title":"Spin Labeling","description":"We present this special topics volume on an area which has not received thorough coverage for over 12 years. Spin Labeling: Theory and Applications represents a complete update on new theoretical aspects and applications of the spin-label method. In the line-shape theory sections, we are especially pleased to include an IBM-compatible diskette supplied by David Schneider and Jack Freed which contains fast, accurate, ready-to-use software for slow-motion simulations. Barney Bales discusses inhomogeneous broadening phenomena in detail. Several developments in techniques and interpretation in saturation transfer spectroscopy have appeared since the publica- tion of Spin Labeling I: Theory and Applications (L. J. Berliner, ed., Academic Press, 1979). We have included an up-to-date chapter on spin-label applications by M. A. Hemminga and P. A. de Jager. By incorporating 15N and deuterium into nitroxide spin labels, several unique advantages are derived in line-shape analysis. Albert Beth and Bruce Robinson have contributed a detailed chapter on the analysis of these labels in the slow-motion regime while Jane Park and Wolfgang Trommer present the advantages for specific biochemical examples in our applications section. Derek Marsh's contri- bution on spin-label spectral analysis may be regarded as a summary chapter which touches on several of the detailed spectral analysis methods described in the earlier chapters.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52124927852817,"sku":"NLS9781461280606","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461280606.jpg?v=1757460491"},{"product_id":"structure-computation-and-dynamics-in-protein-nmr-book-n-rama-krishna-9781475781724","title":"Structure Computation and Dynamics in Protein NMR","description":"Volume 17 is the second in a special topic series devoted to modern techniques in protein NMR, under the Biological Magnetic Resonance series.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52126320820497,"sku":"NLS9781475781724","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781475781724.jpg?v=1757475374"},{"product_id":"in-vivo-spectroscopy-book-lawrence-j-berliner-9780306442766","title":"In Vivo Spectroscopy","description":"In vivo nuclear magnetic and electron spin resonance spectroscopy is concerned, inter alia, with the noninvasive observation of metabolic changes in living systems, including animals and humans. Typically, the physiologi- cal (or pathological) state of an organ or tissue is monitored. This multi- faceted approach was developed during the 1980s. It is still a research technique, but will undoubtedly become a clinical tool. We are proud to present this volume (the eleventh of our series) in which some of the pioneers in this area summarize their contributions and review related literature. Bolinger and Lenkinski describe a variety of localization methods suitable for clinical applications of NMR spectroscopy. Schleich, Caines, and Rydzewski summarize their contributions to approaches involving off-resonance rotating frame relaxation and critically compare these with other NMR techniques that may yield similar information. Chang and James outline their approach and share their experience with the technical aspects 1 31 of H and P NMR spectroscopy and spatially localized spectroscopy in studies of brain ischemia. 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Modern Techniques and Biomedical Applications.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52132233871633,"sku":"NLS9781489976208","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781489976208.jpg?v=1757516090"},{"product_id":"biological-magnetic-resonance-book-lawrence-berliner-9781461565482","title":"Biological Magnetic Resonance","description":"We have now reached our sixth volume in a series which has somewhat unintentionally become an annual event. While we still intend to produce a volume only if a suitable number of excellent chapters in the forefront of biological magnetic resonance are available, our philosophy is to present a pedagogical yet critical description and review of selected topics in mag netic resonance of current interest to the community of biomedical scien tists. This volume fulfills our goals well. As always, we open the volume with a chapter which directly addresses an in vivo biological problem: Phil Bolton's presentation of new techniques in measuring 31 P NMR in cells. Lenkinski's chapter on the theory and applications of lanthanides in protein studies covers the details, highlights, and pitfalls of analysis of these com plexes in biochemical NMR. Reed and Markham summarize the interpreta tion of EPR spectra of manganese in terms of structure and function of proteins and enzymes. Dalton and colleagues describe the applications to biological problems of the relatively new capability of time domain ESR. Finally, we are pleased to offer a departure from mainstream magnetic resonance with the comprehensive and stimulating chapter by Gus Maki on the theory, instrumentation, and applications of optically detected magnetic resonance.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52138427056401,"sku":"NLS9781461565482","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461565482.jpg?v=1757562799"},{"product_id":"biological-magnetic-resonance-book-lawrence-berliner-9781461290209","title":"Biological Magnetic Resonance","description":"We are again proud to present an excellent volume of contemporary topics in NMR and EPR to the biological community. The philosophy behind the volume and the presentation of each chapter remains at the high level reflected in our earlier volumes: to be current, pedagogical, and critical. The first chapters, as always, address a subject related to in-vivo biology. Gabby Elgavish addresses NMR spectroscopy of the intact heart. lain Campbell and colleagues present a state-of-the-art description of NMR methods for probing enzyme kinetics in intact cells and tissues. Klaus Mobius and Wolfgang Lubitz have produced a thorough review of the principles and applications of ENDOR spectroscopy in photobiology and biochemistry including discussions of liquid and solid state ENDOR as well as CIDEP-enhanced ENDOR. The final chapter by Hans Vogel and Sture Forsen addresses a contemporary problem in inorganic biochemistry, namely cation binding to calcium binding proteins. We are pleased to announce that a special forthcoming volume will be devoted entirely to the subject of Spin Labeling: Theory and Applications (3rd compendium). A substantial degree of progress has occurred in this important area of ESR in biology since the last treatise on the subject in 1979. Lastly, we acknowledge our colleagues in the field who continue to support this excellent series both as subscribers and contributors. We pledge to continue servicing the community as long as the need exists.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52139465834769,"sku":"NLS9781461290209","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461290209.jpg?v=1757569149"},{"product_id":"biological-magnetic-resonance-book-lawrence-j-berliner-9781475789027","title":"Biological Magnetic Resonance","description":"This volume constitutes a compilation of the latest experiments  and theories on a rapidly evolving and maturing field in MRI\/MRS,  which is the use of the stable isotope 13-C. The 13-C is used to probe  the chemistry, mechanism, and function in living systems.    All the chapters are written by experts in the field who discuss  topics such as `Tracer Theory and the Suitability of 13-C NMR',  `Applications of 13-C to Studies of Human Brain Metabolism', etc.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52143621669137,"sku":"NLS9781475789027","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781475789027.jpg?v=1757585274"},{"product_id":"carbohydrates-and-nucleic-acids-book-lawrence-j-berliner-9780306440601","title":"Carbohydrates and Nucleic Acids","description":"In the past ten years or so, biological magnetic resonance (NMR and ESR) has fully blossomed and become highly branched. In the 1970s and earlier, a practitioner in biological magnetic resonance was using virtually all of the available methods suitable for his research, with the latter covering a diverse range of systems. Today, the focus of an individual laboratory is actually much narrower, with respect to both the methods and the systems investigated. Thus, those who investigate protein structure by multi- dimensional NMR spectroscopy do not usually engage in studies involving in vivo spectroscopy. The conferences on biological magnetic resonance now have parallel sessions rather than the single, common session of earlier days. Moreover, topical meetings are becoming more frequent. Therefore, this and future volumes of our series will also focus on specific topical areas. We are proud to present Volume 10 of our series. It focuses on Carbohydrates and Nucleic Acids. In an extensive chapter, Kamerling and Vliegenthart use oligosaccharide-alditols released from mucin-type- glycoproteins to illustrate the power of proton NMR spectroscopy in the determination of carbohydrate structure. Wemmer gives a detailed coverage of the arsenal of modern NMR methods now available for structural studies of nucleic acids. Forthcoming volumes will focus on In Vivo Spectroscopy and Protein Structure. As always, we are anxious to get feedback from the readers and hear their comments and suggestions. Lawrence J.","brand":"WoB","offers":[{"title":"GB \/ NEW \/ INGRAM","offer_id":52147426099473,"sku":"NLS9780306440601","price":0.0,"currency_code":"GBP","in_stock":true},{"title":"US \/ NEW \/ INGRAM","offer_id":52734849122577,"sku":"NIN9780306440601","price":0.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9780306440601.jpg?v=1757600499"},{"product_id":"biomedical-epr-part-b-methodology-instrumentation-and-dynamics-book-sandra-s-eaton-9780306485329","title":"Biomedical EPR - Part B: Methodology, Instrumentation, and Dynamics","description":"Focuses on applications of EPR techniques and instrumentation, with applications to dynamics. 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International  experts report the latest developments in NMR  methodology as applied  to strongly relaxed and shifted resonances,  detail the theoretical  aspects of paramagnetic shift and relaxation,  and discuss the  interpretive bases of these molecular properties in  relation to the  structure and function of various paramagnetic  molecules.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52337150689553,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52337151115537,"sku":"NLS9781461362500","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461362500.jpg?v=1758165717"},{"product_id":"distance-measurements-in-biological-systems-by-epr-book-lawrence-j-berliner-9781475705751","title":"Distance Measurements in Biological Systems by EPR","description":"Distance measurements in biological systems by EPR The foundation for understanding function and dynamics of biological systems is knowledge of their structure. Many experimental methodologies are used for determination of structure, each with special utility. Volumes in this series on Biological Magnetic Resonance emphasize the methods that involve magnetic resonance. This volume seeks to provide a critical evaluation of EPR methods for determining the distances between two unpaired electrons. The editors invited the authors to make this a very practical book, with specific numerical examples of how experimental data is worked up to produce a distance estimate, and realistic assessments of uncertainties and of the range of applicability, along with examples of the power of the technique to answer biological problems. The first chapter is an overview, by two of the editors, of EPR methods to determine distances, with a focus on the range of applicability. The next chapter, also by the Batons, reviews what is known about electron spin relaxation times that are needed in estimating distances between spins or in selecting appropriate temperatures for particular experiments. Albert Beth and Eric Hustedt describe the information about spin-spin interaction that one can obtain by simulating CW EPR line shapes of nitroxyl radicals. The information in fluid solution CW EPR spectra of dual-spin labeled proteins is illustrated by Hassane Mchaourab and Eduardo Perozo.","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52337225072913,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52337225662737,"sku":"NLS9781475705751","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781475705751.jpg?v=1758165958"},{"product_id":"spin-labeling-book-lawrence-j-berliner-9780306456442","title":"Spin Labeling","description":"We present here the second issue devoted entirely to the spin-labeling technique as part of Biological Magnetic Resonance. Volume 14 commemorates a modifi- tion in our editorial policy with the retirement of my esteemed coeditor, Jacques Reuben. From thisjuncture into the future, each issue will focus on some special topic in magnetic resonance. Each volume will be organized in most cases by guest editors, for example forthcoming issues will address the following topics: in vivo magnetic resonance (P. Robitaille and L. J. Berliner, eds. ) Modern techniques in proton NMR ofproteins (R. Krishna and L. J. Berliner, eds. ) Instrumental techniques of EPR (C. Bender and L. J. Berliner, eds. ) Thecurrent volume, Spin Labeling: The NextMillennium, presents an excellent collection of techniques and applications that evolved during the past decade since the last volume, volume 8 (1989). Someobvious omissions, such as multiquantum EPR and very high-frequency FT-ESR were unfortunately not possible for this volume. Perhaps they will appear in Spin Labeling: 2001. Lastly it is a pleasure to honor two scientists whose contributions were both pioneering and pivotal to the spin label technique: Professor Eduard G. Rozantsev (Moscow), whose synthetic feats in nitroxyl chemistry set the broad stage for a versatile catalog of labels; and Professor Harden M. McConnell, last year's Int- national ESR (EPR) Society Gold Medalist, who conceived and developed the spin label technique to address many biological problems (proteins, enzymes, m- branes, cells, immune response, etc. ). 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Philip Yeagle presents an eagerly awaited chapter on 31p NMR studies of membranes and membrane protein interactions. Alan Marshall has con- tributed two chapters to the volume: one, with Jiejun Wu, describes magnetic resonance studies of 5S-RNA as probes of its structure and conformation; the secon","brand":"WoB","offers":[{"title":"- \/ - \/ INTERNAL","offer_id":52660165116177,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true},{"title":"GB \/ NEW \/ INGRAM","offer_id":52660166033681,"sku":"NLS9781461565369","price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/9781461565369.jpg?v=1762264641"},{"product_id":"spin-labeling-book-lawrence-j-berliner-9781475780833","title":"Spin Labeling","description":"We present here the second issue devoted entirely to the spin-labeling technique as part of Biological Magnetic Resonance. Volume 14 commemorates a modifi- tion in our editorial policy with the retirement of my esteemed coeditor, Jacques Reuben. From thisjuncture into the future, each issue will focus on some special topic in magnetic resonance. Each volume will be organized in most cases by guest editors, for example forthcoming issues will address the following topics: in vivo magnetic resonance (P. Robitaille and L. J. Berliner, eds. ) Modern techniques in proton NMR ofproteins (R. Krishna and L. J. Berliner, eds. ) Instrumental techniques of EPR (C. Bender and L. J. Berliner, eds. ) Thecurrent volume, Spin Labeling: The NextMillennium, presents an excellent collection of techniques and applications that evolved during the past decade since the last volume, volume 8 (1989). Someobvious omissions, such as multiquantum EPR and very high-frequency FT-ESR were unfortunately not possible for this volume. Perhaps they will appear in Spin Labeling: 2001. 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