This volume is concerned with viral pathogenesis, describing both the development of viral disease and the host/virus interaction. Included are reviews of the life cycle of viruses, the pathology of viral disease, immune responses, and therapeutic applications.
Here is the most complete reference devoted specifically to viral pathogenesis, describing both the development of viral disease and the host/virus interaction. Presenting contributions from leading authorities in this particularly topical field, this comprehensive text exposits the current knowledge on the pathogenesis of viruses, an understanding of which is critical to treatment and prevention of viral diseases. The book opens with a thorough review of principles, covering in detail the life cycle of viruses, including entry, dissemination, shedding and transmission, and replication; the pathology of viral disease, including disease mechanisms, virus virulence, and viral oncogenesis; immune responses, including immune suppression; and therapeutic applications. The second section focuses on experimental pathogenesis, covering detection and quantification of viral genomes, messages, and proteins in tissues and organs; and examining classical and new methods for animal studies. Chapters in the next section, devoted to classical models of viral pathogenesis, cover ectromelia, poliomyelitis, rabies, lymphocytic choriomeningitis virus, avian and murine retroviruses, lentiviruses, and reoviruses. The final section covers systems pathogenesis, emphasizing viral diseases of humans but also drawing on animal studies that elucidate the pathogenesis of human infections
Part I. Principles of Viral Pathogenesis 1. Introduction and History Neal Nathanson 2. Entry, Dissemination, Shedding, and Transmission of Viruses Neal Nathanson and Kenneth L. Tyler 3. Localization of Viral Infections Kathryn V. Holmes 4. Viral Effects on Cellular Functions J. Marie Hardwick and Diane E. Griffin 5. Viral Virulence Neal Nathanson and Grant McFadden 6. Non-Specific Host Responses to Viral Infection Raymond M. Welsh and Ganes Sen 7. Immune Responses to Viral Infection Peter C. Doherty and Rafi Ahmed 8. Virus-Induced Immunopathology Rolf M. Zinkernagel 9. Viral Persistence Rafi Ahmed, Lynda A. Morrison, and David M. Knipe 10. Virus-Induced Immune Suppression Diane E. Griffin 11. Retroviral Oncogenesis Hsing-Jien Kung and Juinn-Lin Liu 12. Small DNA Tumor Viruses Louise T. Chow and Thomas R. Broker 13. Host Susceptibility to Viral Disease Margo A. Brinton 14. Vector Biology in Viral Pathogenesis Scott C. Weaver 15. Evolution of Viral Diseases Neal Nathanson and Frederick A. Murphy 16. Viral Vaccines Gordon Ada 17. Antiviral Agents Martin S. Hirsch, Joan C. Kaplan, and Richard T. D'Aquila Part II. Experimental Pathogenesis 18. An Atlas of Viral Pathogenesis Frederick A. Murphy and Neal Nathanson 19. Methods in Viral Pathogenesis: Tissues and Organs Ashley T. Haase 20. Methods in Viral Pathogenesis: Animals Abigail L. Smith and Stephen W. Barthold 21. Methods in Viral Pathogenesis: Transgenic and Genetically Deficient Mice Glenn F. Rall and Michael B. A. Oldstone Part III. Classic Models of Viral Pathogenesis 22. Mousepox Frank Fenner and R. Mark L. Buller 23. Poliovirus Philip D. Minor 24. Rabies Alan C. Jackson 25. Lymphocytic Choriomeningitis Virus Persephone Borrow and Michael B. A. Oldstone 26. Avian and Murine Retroviruses Harriet L. Robinson, Alan Rein, and Nancy A. Speck 27. Visna-Maedi: The Prototype Lentiviral Disease Opendra Narayan, Sanjay V. Joag, Yahia Chebloune, M.C. Zink, and Janice E. Clements 28. Reovirus Herbert W. Virgin IV, Kenneth L. Tyler, and Terence S. Dermody Part IV. Systems Pathogenesis 29. Viral Respiratory Diseases Peter F. Wright 30. Viral Enteric Diseases Margaret E. Conner and Robert F. Ramig 31. Viral Hepatitis Francis V. Chisari and Carlo Ferrari 32. Viral Hemorrhagic Fevers Clarence J. Peters 33. Viral Infections of the Fetus and Neonate Ann M. Arvin 34. HIV Infection and Associated Diseases William A. O'Brien and Roger J. Pomerantz 35. Viral Diseases of the Central Nervous System: Acute Infections Kenneth L. Tyler and Francisco Gonzalez-Scarano 36. Viral Diseases of the Central Nervous System: Persistent Infections Howard L. Lipton and Donald H. Gilden 37. Prion Diseases Stanley B. Prusiner Inde
Viral Pathogenesis by Neal Nathanson
Used - Good
Lippincott Williams and Wilkins
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The book has been read but remains in clean condition. All pages are intact and the cover is intact. Some minor wear to the spine.