{"product_id":"genetic-effects-on-environmental-vulnerability-to-disease-book-sir-michael-j-rutter-9780470777800","title":"Genetic Effects on Environmental Vulnerability to Disease","description":"Much research has attempted to show direct linear relations between genes and disorder. However, scientists have been discouraged by inconsistent findings based on this simple gene-phenotype approach. The alternative approach is to incorporate information about the environment. A gene-environment interaction approach assumes that environmental pathogens cause disorder, whereas genes influence susceptibility to environmental pathogens.  This book brings together contributions from experts from multiple disciplines who discuss:     How epidemiological cohort studies can better integrate physiological (mechanistic) measures; How best to characterise subjects’ vulnerability versus resilience by moving beyond single genetic polymorphisms; How gene hunters can benefit from recruiting samples selected for known exposures; How environmental pathogens can be used as tools for gene hunting; How to deal with potential spurious (statistical) interactions, and How genes can help explain fundamental demographic properties of disorders (e.g. sex distribution, age effects).","brand":"WoB","offers":[{"title":"GB \/ VERY_GOOD \/ INTERNAL","offer_id":49586765267217,"sku":"GOR013465607","price":110.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4072\/6801\/files\/047077780X.jpg?v=1751260669","url":"https:\/\/www.worldofbooks.com\/products\/genetic-effects-on-environmental-vulnerability-to-disease-book-sir-michael-j-rutter-9780470777800","provider":"World of Books ","version":"1.0","type":"link"}