Neuromethods Series Preface...
Preface...
Table of Contents...
Contributing Authors...
1. Introduction and Overview
Anthony R. White
2. X-Ray Microscopy for Detection of Metals in the Brain
Joanna F. Collingwood and Freddy Adams
3. Imaging Metals in the Brain by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry
Dominic J. Hare, Bence Paul, And Philip A. Doble
4. Fluorescent Probes for the Analysis of Labile Metals in the Brain Cells
Jacek L. Kolanowski, Clara Shen, and Elizabeth J. New
5. Probing Biological Trace Metals with Fluorescent Indicators
Christoph J. Fahrni, Daisy Bourassa, and Ryan Dikdan
6. Microdissection of Brain Tissue to Resolve the Comparative Dissemination of Metal Concentrations in Neurodegenerative Diseases, Focusing on Manganese
Marcus W. Brazier
7. Analysis of Trace Elements and Metalloproteins in Fractionated Human Brain Samples using Size Exclusion Inductively Couples Mass Spectrometry
Adam Gunn and Blaine R. Roberts
8. Size-Fractionation of Metal Species from Serum Samples for Studying Element Biodistribution in Alzheimer's Disease
Raul Gonzalez-Dominguez
9. Lead Uptake and Localization in Glial Cell Cultures
Rola Barhoumi, Robert Taylor, and Evelyn Tiffany-Castiglioni
10. Evaluating Iron Flux in the Brain
Bruce X. Wong, Linh Q. Lam, Andrew Tsatsanis, and James A. Duce
11. Current Methods used to Probe and Quantify Intracellular Total and Free Zn(II) Dynamics, and Subcellular Distribution in Cultured Neurons
Yan Qin, Kyle R. Gee, Qiaoling Jin, Barry Lai, Cheng Qian, and Robert A. Colvin
12. Monitoring Intracellular Zn2+ using Fluorescent Sensors: Facts and Artifacts
Lech Kiedrowski
13. Measuring Changes in Brain Manganese or Iron using Magnetic Resonance Imaging (MRI)
Kimberly L. Desmond and Nicholas A. Bock
14. Treatment and Measurement of Metals in Brain Cell Cultures
Xin Yi Choo and Alexandra Grubman