Aimed at the pathologist specifically, this volume and its companion book bring together a broad spectrum of protocols relevant to the routine molecular analysis of pathological samples. It is written at a level which assumes little previous knowledge of the subject as many people working in clinical pathology laboratories have only limited experience of molecular techniques. Topics in Volume One include those methods which relate to morphological analysis, such as immunocytochemistry, in situ hybridization, chromosome analysis, and flow cytometry. Volume Two demonstrates additional applications of molecular techniques to clinical samples, including the use of PCR, DNA sequencing, and nucleic acid hybridization for such diverse purposes as pathogen identification and forensic studies. Expert guidance and detailed instruction on how to ensure accuracy and reliability for all the protocols is provided.