The research scenario in advanced systems for protecting critical infrastructures and for deeply networked information tools highlights a growing link between security issues and the need for intelligent processing abilities in the area of information s- tems. To face the ever-evolving nature of cyber-threats, monitoring systems must have adaptive capabilities for continuous adjustment and timely, effective response to modifications in the environment. Moreover, the risks of improper access pose the need for advanced identification methods, including protocols to enforce comput- security policies and biometry-related technologies for physical authentication. C- putational Intelligence methods offer a wide variety of approaches that can be fruitful in those areas, and can play a crucial role in the adaptive process by their ability to learn empirically and adapt a system's behaviour accordingly. The International Workshop on Computational Intelligence for Security in Inf- mation Systems (CISIS) proposes a meeting ground to the various communities - volved in building intelligent systems for security, namely: information security, data mining, adaptive learning methods and soft computing among others. The main goal is to allow experts and researchers to assess the benefits of learning methods in the data-mining area for information-security applications. The Workshop offers the opportunity to interact with the leading industries actively involved in the critical area of security, and have a picture of the current solutions adopted in practical domains. This volume of Advances in Soft Computing contains accepted papers presented at CISIS'08, which was held in Genova, Italy, on October 23rd-24th, 2008.