In 1998, Nobel Laureate Dr James Watson, co-discoverer of the structure of DNA, claimed that Dr Judah Folkman would eventually be considered as the 20th-century Darwin for his research into curing cancer. This is a chronicle of Dr Folkman's scientific achievements, and his life. He turned his back on a career in surgery to embark on the lifelong pursuit of a challenging idea. The idea was ridiculed and dismissed, but it appears that it may soon turn the tide against cancer and have an impact on other ailments. Robert Cooke follows Judah Folkman and his staff, and also patients who are on clinical trials, to provide an account of the work being done.