After performing a post-mortem on a young college student who'd been recently treated by a chiropractor, Jack Stapleton, a New York City medical examiner, decides to explore alternative medicine. What makes people seek help from Eastern philosophies or even faith healers to cure their illnesses?

Meanwhile his old college friend, Shawn Doherty, a renowned archaeologist involved in a dig at St Peter's in Rome has made a startling discovery with huge ecclesiastical and medical implications.

When Kevin Murray, another old college, and now Roman Catholic Bishop of New York, gets wind of Shawn's findings he's desperate to keep them from the public and to disassociate himself from Shawn. Kevin turns to his old friend Jack to help protect this explosive secret - one with the power to change lives forever