Bioinformatics and Phylogenetics by Tandy Warnow

Bioinformatics and Phylogenetics by Tandy Warnow

This volume presents a compelling collection of state-of-the-art work in algorithmic computational biology, honoring the legacy of Professor Bernard M.E. Moret in this field. Reflecting the wide-ranging influences of Prof. Moret’s research, the coverage encompasses such areas as phylogenetic tree and network estimation, genome rearrangements, cancer phylogeny, species trees, divide-and-conquer strategies, and integer linear programming. Each self-contained chapter provides an introduction to a cutting-edge problem of particular computational and mathematical interest.

Topics and features: addresses the challenges in developing accurate and efficient software for the NP-hard maximum likelihood phylogeny estimation problem; describes the inference of species trees, covering strategies to scale phylogeny estimation methods to large datasets, and the construction of taxonomic supertrees; discusses the inference of ultrametric distances from additive distance matrices, and the inference of ancestral genomes under genome rearrangement events; reviews different techniques for inferring evolutionary histories in cancer, from the use of chromosomal rearrangements to tumor phylogenetics approaches; examines problems in phylogenetic networks, including questions relating to discrete mathematics, and issues of statistical estimation; highlights how evolution can provide a framework within which to understand comparative and functional genomics; provides an introduction to Integer Linear Programming and its use in computational biology, including its use for solving the Traveling Salesman Problem.

Offering an invaluable source of insights for computer scientists, applied mathematicians, and statisticians, this illuminating volume will also prove useful for graduate courses on computational biology and bioinformatics.

The book is mainly aimed at researchers with pre-existing knowledge of phylogenetics and computational approaches related to it (eg. graph theory). The numerous examples make this collection of chapters comprehensible for undergraduate, graduate and postgraduate researchers from computer science, mathematics and biology; the extensive set of references that accompany every chapter recommend the book as a reliable starting point for further studies. (Irina Ioana Mohorianu, zbMATH 1429.92003, 2020)

Warnow, Tandy: - Tandy Warnow is a Founder Professor of Engineering at the University of Illinois, Urbana-Champaign. Her awards include the National Science Foundation Young Investigator Award (1994), the David and Lucile Packard Foundation Award in Science and Engineering (1996), a Radcliffe Institute for Advanced Study Fellowship (2003), and a John Simon Guggenheim Memorial Foundation Fellowship (2011). She was elected a Fellow of the Association for Computing Machinery (ACM) in 2015, and of the International Society for Computational Biology (ISCB) in 2017.

SKU	Unavailable
ISBN 13	9783030108366
ISBN 10	3030108368
Title	Bioinformatics and Phylogenetics
Author	Tandy Warnow
Series	Computational Biology
Condition	Unavailable
Binding Type	Hardback
Publisher	Springer Nature Switzerland AG
Year published	2019-04-17
Number of pages	410
Cover note	Book picture is for illustrative purposes only, actual binding, cover or edition may vary.