Dead Men Living by Brian Freemantle

Dead Men Living by Brian Freemantle

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Dead Men Living by Brian Freemantle

Dopamine receptors are among the most validated drug targets for neuropsychiatric disorders such as schizophrenia and Parkinson's disease, and are potential targets for other disorders such as substance abuse, depression, Tourette's syndrome, and attention deficit hyperactivity disorder. The new knowledge brought from the creation and characterization of mice deficient in each of the subtypes and the development of increasingly subtype-selective agonists and antagonists has fueled many of the chapters new to this second edition, with the use of knock-out mice and subtype-selective drugs meriting discussion in stand-alone chapters. The field of G protein-coupled receptors has also advanced significantly since the first edition, with a model of GPCR signaling based on linear, compartmentalized pathways having been replaced by a more complex, richer model in which neurotransmitter effects are mediated by a signalplex composed of numerous signaling proteins, including multiple GPCRs, other types of receptors, such as ionotropic receptors, accessory and scaffolding proteins, and effectors. This second edition of Dopamine Receptors will be of interest to neurobiologists, pharmacologists and molecular biologists who study the brain, as well as neurologists working on psychiatric diseases.

Freemantle, Brian: - BRIAN FREEMANTLE is the author more than thirty books, which have sold more than ten million copies worldwide. These include fifteen previous novels in the Charlie Muffin series. He has been foreign editor and chief foreign correspondent for the London Daily Mail and foreign correspondent for the London Daily Sketch, among others. He lives in England.
SKU Unavailable
ISBN 13 9780312243791
ISBN 10 0312243790
Title Dead Men Living
Author Brian Freemantle
Series Charlie Muffin Thrillers
Condition Unavailable
Binding Type Hardback
Publisher St. Martin's Press
Year published 2000-06-01
Number of pages 336
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
Note Unavailable