Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials by Andrew P Grieve

Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials by Andrew P Grieve

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Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials by Andrew P Grieve

This book provides a practical introduction to unconditional approaches to planning randomised clinical trials, particularly aimed at drug development in the pharmaceutical industry. This book is aimed at providing guidance to practitioners in using average power, assurance and related concepts.

"This is a graduate level/practitioner book in ten chapters covering expected, average and predicted power, assurance and Bayesian power followed by a shift in focus to priors, interim predictions and multiple decision criteriaThe final chapter looks at surety. The book is logically laid out, with formulae for the normal theory case, some examples, and helpful figures."
~Maia Lesosky, ISCB Book Reviews

Andrew P. Grieve is a Statistical Research Fellow in the Centre of Excellence in Statistical Innovation at UCB Pharma. He is a former Chair of PSI (Statisticians in the Pharmaceutical Industry) and a past-President of the Royal Statistical Society. He has over 45 years of experience as a biostatistician working in the pharmaceutical industry and academia and has been active in most areas of pharmaceutical R&D in which statistical methods and statisticians are intimately involved, including drug discovery, pre-clinical toxicology, pharmaceutical development, pharmacokinetics and pharmacodynamics, phase I–IV of clinical development, manufacturing, health economics and clinical operations.

SKU Unavailable
ISBN 13 9781032111315
ISBN 10 1032111313
Title Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials
Author Andrew P Grieve
Series Chapman And Hall Crc Biostatistics Series
Condition Unavailable
Binding Type Paperback
Publisher Taylor & Francis Ltd
Year published 2024-08-26
Number of pages 188
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
Note Unavailable