Preclinical Drug Development by Mark Rogge
Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include: Pharmacokinetics Modeling and simulation Formulation and routes of administration Toxicity evaluations The assessment of drug absorption and metabolism Interspecies scaling Lead molecule selection and optimization via profiling Screening using in silico and in vitro toxicity evaluations The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.| SKU | Unavailable |
| ISBN 13 | 9781420084726 |
| ISBN 10 | 1420084720 |
| Title | Preclinical Drug Development |
| Author | Mark Rogge |
| Series | Drugs And The Pharmaceutical Sciences |
| Condition | Unavailable |
| Publisher | Taylor & Francis Inc |
| Year published | 2009-09-25 |
| Number of pages | 380 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
| Note | Unavailable |