Dina and Julia first meet at a surgical convention and bond over frustrations with their husbands' demanding schedules. But geography, time, and growing families make maintaining their friendship difficult and their relationship eventually falls apart. One of them is left to wonder why; the other has a secret. But neither of them knows that decisions made by family members decades earlier have set them on a collision course.

Years after their friendship ends, Julia gets word that her daughter has suddenly become seriously ill-and she and Dina must decide whether they can face the history that now unites them and muster the maturity to rescue their emotionally tattered families.

A sweeping saga that follows generations from a shtetl in Odessa to the comforts of Scarsdale, an uprising in Glasgow to servitude in the Caribbean, and a trek through the Alps to a displaced persons camp in Italy, The Convention of Wives is a story about the ever-evolving messiness of friendship and marriage, and the wonder of survival.