In this issue of Obstetrics and Gynecology Clinics of North America, guest editors Drs. Kevin A. Ault and Alisa Kachikis bring their considerable expertise to the topic of Infectious Diseases in Obstetrics and Gynecology. Changes in immune function during pregnancy may cause an increased risk of infection, and if left untreated, may lead to serious complications. In this issue, top experts provide state-of-the-art clinical information on managing infections in pregnancy with the goal of protecting both mother and fetus. Contains 16 practice-oriented topics including cytomegalovirus; COVID vaccines during pregnancy; an update on chlamydia and gonorrhea; hepatitis C during pregnancy; syphilis; vaccine hesitancy; pathogenesis of COVID during pregnancy; emerging infectious diseases; and more. Provides in-depth clinical reviews on infectious diseases in obstetrics and gynecology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.