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Chemistry of Bioconjugates Ravin Narain

Chemistry of Bioconjugates By Ravin Narain

Chemistry of Bioconjugates by Ravin Narain


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Summary

Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. This book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials.

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Chemistry of Bioconjugates Summary

Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications by Ravin Narain

Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. With its emphasis on synthesis, properties and applications, this book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials. Its detailed descriptions of methods make it possible for researchers to fabricate and take full advantage of bioconjugates for a broad range of applications. Moreover, the book sets the foundation for the development of new applications, including assays, imaging, biosensors, drug delivery, and diagnostics. Chemistry of Bioconjugates features contributions from an international team of leading experts and pioneers in the field. These contributions reflect the authors firsthand laboratory experience as well as a thorough review of the current literature. The book s six sections examine: * General methods of bioconjugation * Polymer bioconjugates * Organic nanoparticle-based bioconjugates * Inorganic nanomaterial bioconjugates, including metals and metal oxides * Cell-based, hydrogel/microgel, and glyco-bioconjugates * Characterization, physico-(bio)chemical properties, and applications of bioconjugates This comprehensive exploration of bioconjugates includes discussions of polymers, dendrimers, lipids, nanoparticles, and nanotubes. References at the end of each chapter serve as a gateway to the most important original research findings and reviews in the field. By drawing together and analyzing all the latest chemical methods and research findings on the physico-chemical and biochemical properties of bioconjugates, Chemistry of Bioconjugates sheds new light on the significance and potential of bioconjugation. The book is recommended for organic and polymer chemists, biochemists, biomaterial scientists, carbohydrate chemists, biophysicists, bioengineers, and drug and gene delivery scientists.

About Ravin Narain

RAVIN NARAIN, PhD, is Associate Professor in the Department of Chemical and Materials Engineering at the University of Alberta. He has published more than 100 articles in peer-reviewed journals and is the editor of Engineered Carbohydrate-Based Materials for Biomedical Applications (Wiley). Dr. Narain s research examines nanomedicine and regenerative medicine, with an emphasis on developing new biomaterials for gene delivery and tissue engineering.

Table of Contents

PREFACE vii CONTRIBUTORS ix SECTION I GENERAL METHODS OF BIOCONJUGATION 1 Covalent and Noncovalent Bioconjugation Strategies 3 Rajesh Sunasee and Ravin Narain SECTION II POLYMER BIOCONJUGATES 2 Bioconjugates Based on Poly(Ethylene Glycol)s and Polyglycerols 79 Rajesh A. Shenoi, Fang Gao, Muhammad Imran ul-Haq, and Jayachandran N. Kizhakkedathu 3 Synthetic Polymer Bioconjugate Systems 104 Marya Ahmed and Ravin Narain 4 Natural Polymer Bioconjugate Systems 133 Lichao Liu, Xiuwei Pan, and Weian Zhang 5 Dendrimer Bioconjugates: Synthesis and Applications 146 Ali Nazemi and Elizabeth R. Gillies SECTION III ORGANIC NANOPARTICLES BASED BIOCONJUGATES 6 Bioconjugation Strategies: Lipids, Liposomes, Polymersomes, and Microbubbles 187 Anirban Sen Gupta and Horst A. von Recum 7 Organic Nanoparticle Bioconjugate: Micelles, Cross-Linked Micelles, and Nanogels 203 Maria Vamvakaki 8 Carbon Nanotubes and Fullerene C60 Bioconjugates 239 Keshwaree Babooram and Ravin Narain SECTION IV INORGANIC NANOMATERIALS BIOCONJUGATES (METALS, METAL OXIDES QUANTUM DOTS, IRON-OXIDE) 9 Gold Nanomaterials Bioconjugates 257 Qian Yang 10 Methods for Magnetic Nanoparticle Synthesis and Functionalization 281 Mohammad H. El-Dakdouki, Kheireddine El-Boubbou, Jingguang Xia, Herbert Kavunja, and Xuefei Huang 11 Quantum Dots Bioconjugates 315 Xiaoze Jiang, Meifang Zhu, and Ravin Narain 12 Silica Nanoparticle Bioconjugates 327 Yohei Kotsuchibashi, Mitsuhiro Ebara, and Ravin Narain 13 Polyhedral Oligomeric Silsesquioxanes (POSS) Bioconjugates 344 Weian Zhang, Zhenghe Zhang, and Lizhi Hong SECTION V CELL-BASED, HYDROGELS/MICROGELS AND GLYCO-BIOCONJUGATES 14 Cell-Based Bioconjugates 357 Mitsuhiro Ebara 15 Bioresponsive Hydrogels and Microgels 370 Xue Li and Michael J. Serpe 16 Conjugation Strategies Used for the Preparation of Carbohydrate-Conjugate Vaccines 387 Rachel Hevey and Chang-Chun Ling SECTION VI CHARACTERIZATION, PHYSICO-(BIO)CHEMICAL PROPERTIES, AND APPLICATIONS OF BIOCONJUGATES 17 Properties and Characterization of Bioconjugates 417 Ali Faghihnejad, Jun Huang, and Hongbo Zeng 18 Physico-Chemical and Biochemical Properties of Bioconjugates 431 Marya Ahmed and Ravin Narain 19 Applications of Bioconjugates 444 Marya Ahmed and Ravin Narain INDEX 457

Additional information

CIN1118359143G
9781118359143
1118359143
Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications by Ravin Narain
Used - Good
Hardback
John Wiley & Sons Inc
20140325
496
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in good condition, but if you are not entirely satisfied please get in touch with us

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