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Circadian Rhythms and Biological Clocks Part A Volume editor Amita Sehgal (John Herr Musser Professor of Neuroscience co-Director, Penn Medicine Neuroscience Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA)

Circadian Rhythms and Biological Clocks Part A By Volume editor Amita Sehgal (John Herr Musser Professor of Neuroscience co-Director, Penn Medicine Neuroscience Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA)

Circadian Rhythms and Biological Clocks Part A by Volume editor Amita Sehgal (John Herr Musser Professor of Neuroscience co-Director, Penn Medicine Neuroscience Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA)

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Circadian Rhythms and Biological Clocks Part A Summary

Circadian Rhythms and Biological Clocks Part A: Volume 551 by Volume editor Amita Sehgal (John Herr Musser Professor of Neuroscience co-Director, Penn Medicine Neuroscience Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA)

Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems. Protocols are provided to assess clock function, entrainment of the clock to stimuli such as light and food, and output rhythms of behavior and physiology. This volume also delves into the impact of circadian disruption on human health. Contributions are from leaders in the field who have made major discoveries using the methods presented here.

Circadian Rhythms and Biological Clocks Part A Reviews

...these volumes provide a remarkable summary of the methods, experimental systems, and findings of cutting-edge research into circadian rhythms....an essential resource for all types of scientists studying chronobiology, as well as an informative read for anyone who wishes to understand better the ticking of their biological clock. --The Quarterly Review of Biology Praise for the Series: Should be on the shelves of all libraries in the world as a whole collection. --Chemistry in Industry The work most often consulted in the lab. --Enzymologia The Methods in Enzymology series represents the gold-standard. --Neuroscience

About Volume editor Amita Sehgal (John Herr Musser Professor of Neuroscience co-Director, Penn Medicine Neuroscience Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA)

Dr. Sehgal is the John Herr Musser Professor of Neuroscience and Director of a Program in Chronobiology at the Perelman School of Medicine, University of Pennsylvania. She has also been an Investigator of the Howard Hughes Medical Institute since 1997. Dr. Sehgal received her Ph.D. from the Graduate School of Medical Sciences, Cornell University, working with Dr. Moses Chao, and conducted her postdoctoral work with Dr. Michael Young at Rockefeller University. A major focus in her laboratory is the cellular and molecular basis of circadian rhythms, using the fruit fly, Drosophila melanogaster as a model system. Her laboratory also developed a Drosophila model for the study of sleep, which has been adopted by laboratories worldwide, and is rapidly provding insight into the regulation and function of sleep. In 2009, Dr. Sehgal was elected to the Institute of Medicine and in 2011 to the American Academy of Arts and Sciences.

Table of Contents

1. Studying Circadian Rhythm and Sleep Using Genetic Screens in Drosophila Sofia Axelrod, Lino Saez and Michael W. Young 2. Dissecting the Mechanisms of the Clock in Neurospora Jennifer Hurley, Jennifer J. Loros and Jay C. Dunlap 3. High Throughput and Quantitative Approaches for Measuring Circadian Rhythms in Cyanobacteria Using Bioluminescence Ryan K. Shultzaberger, Mark L. Paddock, Takeo Katsuki, Ralph J. Greenspan and Susan S. Golden 4. Using Circadian Entrainment to Find Cryptic Clocks Zheng Eelderink-Chen, Maria Olmedo, Jasper Bosman and Martha Merrow 5. Wavelet-based Analysis of Circ adian Behavioral Rhythms Tanya L. Leise 6. Genetic Analysis of Drosophila Circadian Behavior in Semi-Natural Conditions Edward W Green, Emma K O'Callaghan, Mirko Pegoraro, J Douglas Armstrong, Rodolfo Costa3 and Charalambos P Kyriacou 7. Methods to Study Molecular Mechanisms of the Neurospora Circadian Clock Joonseok Cha, Mian Zhou, and Yi Liu 8. Detecting KaiC Phosphorylation Rhythms of the Cyanobacterial Circadian Oscillator in Vitro and in Vivo Yong-Ick Kim, Joseph S. Boyd, Javier Espinosa, and Susan S. Golden 9. The Role of Casein Kinase I in the Drosophila Circadian Clock Jeffrey L. Price, Jin-Yuan Fan, Andrew Keightley and John C. Means 10. Purification and Analysis of PERIOD Protein Complexes of the Mammalian Circadian Clock Jin Young Kim, Pieter Bas Kwak, Michael Gebert, Hao A. Duong and Charles J. Weitz 11. Best Practices for Fluorescence Microscopy of the Cyanobacterial Circadian Clock Susan E. Cohen, Marcella L. Erb, Joe Pogliano and Susan S. Golden 12. Structural and Biophysical Methods to Analyze Clock Function and Mechanism Martin Egli 13. Identification of Small Molecule Modulators of the Circadian Clock Tsuyoshi Hirota and Steve A. Kay 14. ChIP-Seq and RNA-Seq Methods to Study Circadian Control of Transcription in Mammals Joseph S. Takahashi, Vivek Kumar , Prachi Nakashe, Nobuya Koike, Hung-Chung Huang, Carla B. Green, and Tae-Kyung Kim 15. Chipping away at the Drosophila Clock Jian Zhou, Wangjie Yu and Paul E. Hardin 16. Considerations for RNA-seq Analysis of Circadian Rhythms Jiajia Li, Gregory R Grant, John B Hogenesch and Michael E Hughes 17. RNA-Seq Profiling of Small Numbers of Drosophila Neurons Katharine Abruzzi, Xiao Chen, Emi Nagoshi, Abby Zadina, and Michael Rosbash 18. Analysis of Circadian Regulation of Poly(A) Tail Length Shihoko Kojima and Carla B. Green 19. Sample Preparation for Phosphoproteomic Analysis of Circadian Time Series in Arabidopsis Thaliana Johanna Krahmer, Matthew M Hindle, Sarah F Martin, Thierry Le Bihan and Andrew J Millar

Additional information

NPB9780128012185
9780128012185
0128012188
Circadian Rhythms and Biological Clocks Part A: Volume 551 by Volume editor Amita Sehgal (John Herr Musser Professor of Neuroscience co-Director, Penn Medicine Neuroscience Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA)
Volume editor Amita Sehgal (John Herr Musser Professor of Neuroscience co-Director, Penn Medicine Neuroscience Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA)
New
Hardback
Elsevier Science Publishing Co Inc
2015-01-27
488
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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