56 Thoughts from 56 Hope Road by Cedella Marley

56 Thoughts from 56 Hope Road by Cedella Marley

Over the last half of century interferon (IFN), originally discovered as an antiviral protein, has developed from an inhibitor of viral replication to a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes and has shown an unexpected complexity of type I IFN genes and their expression. Presently, some aspects of the of the pathogen mediated induction of IFN gene expression are understood at molecular level, while others are still at the stage of description. Both Toll like receptors and cytoplasmic RNA helicases were shown to recognize viral nucleic acids and the basis of a distinct recognition of viral nucleic acids from the cellular ones are emerging. Important insights on the virus recognition entity, leading to the expression of interferon and interferon induced genes, have been made in the recent year, which are challenging the accepted concept of the critical role of dsRNA in IFN induction. The availability of genetically modified mice that are lacking either essential components of the interferon inducing pathway, or interferon signaling pathway fully confirmed the original idea, made soon after its discovery, that interferon is the first cellular defense against viral infection.

Hausman, Gerald: - GERALD HAUSMAN, the author of more than 70 books for children and adults spent much of his adult life in New Mexico during which time he translated Native origin stories with Navajo artist and friend, Jay DeGroat. Many of these were aired on Navajo Nation radio station KTNN and The Turquoise Horse was included in the Junior Great Books international reading program. It is used in classrooms throughout the U.S. and in the twenty years since its first publication has become a classic in cultural learning for elementary and middle school students. His folktales have also been aired on the History Channel, NPR, and Pacifica Broadcasting. In 2006 the University of Washington Graduate Film School, (supported by Myra and Bill Gates Foundation and Pixar) created an animated short from Gerald Hausman's book, The Boy with the Sun Tree Bow. It has been used as a textbook for environmental studies in South America. Twelve of Gerald's other books are translated in foreign languages and The New York Times praised the anthology Tunkashila: From the Birth of Turtle Island to the Blood of Wounded Knee calling it An eloquent tribute to the first great storytellers of America. Other honors for Gerald Hausman's work are from the American Folklore Society, the American Bookseller, Children's Protective Services, the Bank Street College of Education, the National Council of Social Studies, the International Reading Association, Parent's Choice, The Ministry of Education of Jamaica, The New York Public Library Best Books, and CCBC Choices/Best of the Year. Gerald and his wife Loretta have done a number of animal books together and with Alice Winston Carney they have led a summer workshop in memoir writing at The Plaza Hotel in Las Vegas, New Mexico, for the past nine years. Gerald and Loretta also founded Irie Books which publishes memoirs, children's books, poetry, biography and translations. Gerald's most recent book is Island Dreams: Selected Poems from 1964-2015. He has read his poetry at Harvard University, St John's College, the Kennedy Center, Fordham University, Queen's College and dozens of other universities nationwide.

SKU	Unavailable
ISBN 13	9780971975804
ISBN 10	0971975809
Title	56 Thoughts from 56 Hope Road
Author	Cedella Marley
Condition	Unavailable
Binding Type	Paperback
Publisher	Hampton Roads Publishing Co
Year published	2003-03-12
Number of pages	88
Cover note	Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
Note	Unavailable